Results 61 to 70 of about 3,522,828 (292)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Intrapulmonary percussive ventilation improves the outcomes of helmet ventilation

open access: yesAustralian Journal of Physiotherapy, 2007
Questions In adults with an acute exacerbation of chronic obstructive pulmonary disease (COPD) receiving non-invasive positive pressure ventilation (NIV), is intrapulmonary percussive ventilation (IPV) feasible? Does IPV improve outcomes compared to manual airway clearance techniques?
openaire   +2 more sources

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

open access: yesArthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos   +2 more
wiley   +1 more source

Efficacy and safety of an open lung ventilation strategy with staircase recruitment followed by comparison on two different modes of ventilation, in moderate ARDS in cirrhosis: A pilot randomized trial

open access: yesCanadian Journal of Respiratory Therapy, 2021
Background Mechanical ventilation in cirrhosis with acute respiratory distress syndrome (ARDS) is not widely studied. We aimed to study the effect of the staircase recruitment manoeuvre followed by two different modes of ventilation.
Vibha Goel   +5 more
doaj   +1 more source

Natural ventilation and cooling by evaporation in hot-arid climates [PDF]

open access: yes, 1990
In hot climates, outside air is too hot during the day. In hot arid climates, low humidity increases discomfort. For comfort, hot air should be cooled before flowing into dwellings and moisture in the moving air increased.
Aboul Naga, Mohsen M
core   +4 more sources

Non-invasive ventilation at the front door: a service improvement

open access: yesFuture Healthcare Journal
Background: Commencing non-invasive ventilation (NIV) promptly at the front door is crucial in patients presenting with acute exacerbations of chronic obstructive pulmonary disease (COPD) complicated by acute hypercapnic respiratory failure.1 Studies ...
Rehab Haider   +5 more
doaj   +1 more source

Simulation of the effect of horizontal airflow channel on natural ventilation in apartments [PDF]

open access: yesE3S Web of Conferences
Natural ventilation has an important impact on people's work and life. Reasonable use of natural ventilation can effectively improve indoor air quality and thermal comfort, reduce the use of air conditioning and reduce energy consumption.
Yu Xichen, Cheng Mingyuan
doaj   +1 more source

Programmed multi-level ventilation in COVID-19-related acute respiratory distress syndrome: a multi-center retrospective observational study

open access: yesJournal of International Medical Research, 2022
Objective We evaluated pressure-controlled ventilation (PCV) with multiple programmed levels of positive end expiratory pressure (programmed multi-level ventilation; PMLV) in patients with coronavirus disease 2019 (COVID-19)-related acute respiratory ...
Filip Depta   +11 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

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