Results 61 to 70 of about 3,522,828 (292)
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Intrapulmonary percussive ventilation improves the outcomes of helmet ventilation
Questions In adults with an acute exacerbation of chronic obstructive pulmonary disease (COPD) receiving non-invasive positive pressure ventilation (NIV), is intrapulmonary percussive ventilation (IPV) feasible? Does IPV improve outcomes compared to manual airway clearance techniques?
openaire +2 more sources
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos +2 more
wiley +1 more source
Background Mechanical ventilation in cirrhosis with acute respiratory distress syndrome (ARDS) is not widely studied. We aimed to study the effect of the staircase recruitment manoeuvre followed by two different modes of ventilation.
Vibha Goel +5 more
doaj +1 more source
Natural ventilation and cooling by evaporation in hot-arid climates [PDF]
In hot climates, outside air is too hot during the day. In hot arid climates, low humidity increases discomfort. For comfort, hot air should be cooled before flowing into dwellings and moisture in the moving air increased.
Aboul Naga, Mohsen M
core +4 more sources
Non-invasive ventilation at the front door: a service improvement
Background: Commencing non-invasive ventilation (NIV) promptly at the front door is crucial in patients presenting with acute exacerbations of chronic obstructive pulmonary disease (COPD) complicated by acute hypercapnic respiratory failure.1 Studies ...
Rehab Haider +5 more
doaj +1 more source
Simulation of the effect of horizontal airflow channel on natural ventilation in apartments [PDF]
Natural ventilation has an important impact on people's work and life. Reasonable use of natural ventilation can effectively improve indoor air quality and thermal comfort, reduce the use of air conditioning and reduce energy consumption.
Yu Xichen, Cheng Mingyuan
doaj +1 more source
Objective We evaluated pressure-controlled ventilation (PCV) with multiple programmed levels of positive end expiratory pressure (programmed multi-level ventilation; PMLV) in patients with coronavirus disease 2019 (COVID-19)-related acute respiratory ...
Filip Depta +11 more
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source

