Results 41 to 50 of about 4,736,339 (290)

Bayesian statistics: a primer for perioperative medicine clinicians

open access: yesPerioperative Medicine
Bayesian methods offer an intuitive and coherent statistical framework for updating probabilistic beliefs by integrating prior knowledge—whether from existing data or expert consensus—with new evidence via likelihood functions to generate posterior ...
Guido Mazzinari   +5 more
doaj   +1 more source

A combined method for the analysis of mine ventilation networks

open access: yes, 2018
Solving ventilation networks of natural splitting is a basic problem in mine ventilation. Several mathematical techniques are used to solve this problem. This paper proposes a new method which combines the advantages of both classical Hardy Cross method and unconstrained optimisation techniques.
SARAÇ, Saim, ŞENSÖĞÜT, Cem
openaire   +3 more sources

A dynamic ventilation model for gravity sewer networks

open access: yesWater Science and Technology, 2012
To implement any effective odour and corrosion control technology in the sewer network, it is imperative that the airflow through gravity sewer airspaces be quantified. This paper presents a full dynamic airflow model for gravity sewer systems. The model, which is developed using the finite element method, is a compressible air transport model.
Y C, Wang   +3 more
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Parameterization of a ventilation network model for the analysis of mine working emergency ventilation modes

open access: yesGornye nauki i tekhnologii = Mining Science and Technology (Russia), 2023
Digital simulation of mine fires and explosions is an important stage in the process of developing technical solutions and measures aimed at improving the safety of personnel involved in underground mining. Correct simulation results determine the effectiveness of decisions in the event of an actual emergency situation.
M. O. Perestoronin   +2 more
openaire   +2 more sources

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

The PROtective VEntilation (PROVE) Network - advancing research and collaboration in mechanical ventilation

open access: yesCritical Care Science
The PROtective VEntilation (PROVE) Network is a globally-recognized collaborative research group dedicated to advancing research, education, and collaboration in the field of mechanical ventilation. Established to address critical questions in intraoperative and intensive care ventilation, the network focuses on improving outcomes for patients ...
Marcus J. Schultz   +20 more
openaire   +3 more sources

Split-ventilation for more than one patient, can it be done? Yes

open access: yes, 2020
Original research regarding ventilating two patients with one ventilator (split-ventilation) for COVID ...
Cabbat, Robert   +9 more
core   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

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