Results 131 to 140 of about 3,855 (162)

Unraveling Ventilator‐Induced Diaphragmatic Dysfunction: A Comprehensive Narrative Review on Pathogenesis, Diagnosis and Management of Ventilator‐Induced Diaphragmatic Dysfunction

Physiotherapy Research International
ABSTRACTIntroduction: Mechanical ventilation (MV) is a crucial intervention for patients with respiratory failure to ensure optimal gas exchange. However, there is strong evidence that MV exerts significant structural and functional alterations on the diaphragm, leading to a notable decline in its contractile force and the consequent atrophy of its ...
Sajad Ahmad, Khwaja, Mohammad Anwar, Habib, Rajesh, Gupta, Harjit Singh, Mahay, Deepika, Singla   +4 more
exaly   +3 more sources

Assist–Control Mechanical Ventilation Attenuates Ventilator-induced Diaphragmatic Dysfunction

American Journal of Respiratory and Critical Care Medicine, 2004
Abstract Controlled mechanical ventilation induced a profound diaphragm muscle dysfunction and atrophy. The effects of diaphragmatic contractions with assisted mechanical ventilation on diaphragmatic isometric, isotonic contractile properties, or the expression of muscle atrophy factor-box (MAF-box), the gene responsible for muscle ...
Vincent J Caiozzo
exaly   +3 more sources

Relationship between Autophagy and Ventilator-induced Diaphragmatic Dysfunction

Anesthesiology, 2015
AbstractAbstract Autophagy was rapidly induced in the diaphragm in a mouse model of ventilator-induced diaphragmatic dysfunction, but the autophagic process was not responsible for diaphragmatic weakness. Background: Mechanical ventilation (MV) is associated with atrophy and weakness of the diaphragm muscle,
Azuelos, Ilan, Jung, Boris, Picard, Martin, Li, Feng, Li, Tong, Lemaire, Christian, Giordano, Christian, Hussain, Sabah, Petrof, Basil   +8 more
openaire   +2 more sources

Trolox Attenuates Mechanical Ventilation–induced Diaphragmatic Dysfunction and Proteolysis

American Journal of Respiratory and Critical Care Medicine, 2004
Abstract Prolonged mechanical ventilation results in diaphragmatic oxidative injury, elevated proteolysis, fiber atrophy, and reduced force-generating capacity. We tested the hypothesis that antioxidant infusion during mechanical ventilation would function as an antioxidant to maintain redox balance within diaphragm muscle fibers and ...
Jenna L, Betters, David S, Criswell, R Andrew, Shanely, Darin, Van Gammeren, Darin, Falk, Keith C, Deruisseau, Melissa, Deering, Tossaporn, Yimlamai, Scott K, Powers   +8 more
openaire   +2 more sources

Ventilator-induced diaphragmatic dysfunction in extremely preterm infants: a pilot ultrasound study

European Journal of Pediatrics, 2023
To investigate the development of diaphragmatic dysfunction in ventilated extremely preterm infants (EPI) using diaphragm ultrasound (DU). EPI of less than 28 weeks' gestational age who required mechanical ventilation within six hours of birth were included in this prospective, observational study.
Yusuke Hoshino, Junichi Arai, Koji Hirono, Kazushi Maruo, Rena Miura-Fuchino, Yoshiya Yukitake, Daigo Kajikawa, Tae Kamakura, Ayako Hinata   +8 more
openaire   +2 more sources

[Ventilator-induced diaphragmatic dysfunction (VIDD)].

Pneumologie (Stuttgart, Germany), 2008
Although life-saving, mechanical ventilation is associated with numerous complications. Recently, it was shown in animal models that controlled mechanical ventilation (CMV) can cause the so-called ventilator-induced diaphragmatic dysfunction (VIDD). The decrease in diaphragmatic strength proceeds along with prolonged mechanical ventilation.
K, Schild, C, Neusch, B, Schönhofer
openaire   +1 more source

Impact of Sedation on Ventilator‐Induced Diaphragmatic Dysfunction in Extremely Preterm Infants

Pediatric Pulmonology
ABSTRACT Background Ventilator‐induced diaphragmatic dysfunction is associated with poor patient outcomes. However, the detailed pathophysiology and risk factors underlying the exacerbation of diaphragmatic dysfunction remain unclear. We aimed to evaluate the effect of sedation on diaphragmatic
Yusuke Hoshino, Junichi Arai, Koji Hirono, Kazushi Maruo, Rena Miura‐Fuchino, Yoshiya Yukitake, Daigo Kajikawa, Tae Kamakura, Ayako Hinata, Yuki Okada, Yoshihiro Sato   +10 more
openaire   +2 more sources

Spontaneous breathing intensity is related with the severity of ventilator-induced diaphragmatic dysfunction

Acute critical care, 2019
Purpose: To determine whether there is a certain relationship between spontaneous breathing intensity and the severity of ventilator-induced diaphragmatic dysfunction (VIDD) and which spontaneous breathing intensity could effectively prevent VIDD.
Zujin Luo, Silu Han, Yan Wang, Sijie Liu, Wei Sun, Baosen Pang, Jiawei Jin, Zhixin Cao, Yingmin Ma   +8 more
openaire   +1 more source

[Understanding ventilator-induced diaphragmatic dysfunction (VIDD): progress and advances].

Pneumologie (Stuttgart, Germany), 2014
There is rising evidence that ventilator-induced diaphragmatic dysfunction (VIDD) is not just an artifactual finding from animal studies, but actually occurs in humans undergoing invasive mechanical ventilation. Initial research findings in humans have demonstrated that periods of controlled invasive mechanical ventilation lasting just 18 - 69 hours ...
H-J, Kabitz, W, Windisch, B, Schönhofer
openaire   +1 more source

Ventilator-induced diaphragmatic vascular dysfunction*

Critical Care Medicine, 2012
Ercheng, Zhu, Catherine S H, Sassoon
openaire   +2 more sources