Results 61 to 70 of about 97,347 (154)

When serious becomes critical

Journal of Hospital Medicine, EarlyView.
Yohei Masuda
wiley   +1 more source

Experimental Extracorporeal Circulation System: A Pilot Study in Rats

Artificial Organs, EarlyView.
A miniature extracorporeal circulation (ECC) system was developed for reproducible rodent studies. This system incorporates an integrated heat exchanger and a silicone membrane oxygenator within a double‐lumen circuit, resulting in an ultralow priming volume of < 1.5 mL.
Akira T. Kawaguchi, Kaori Inukai, Mayuko Shibata, Gen T. Kawaguchi, Kazuaki Sato, Taiga Aburaya, Jacob Bergsland, Yoshiyuki Yamada   +7 more
wiley   +1 more source

Novel mechanical ventilator weaning predictive model

Kaohsiung Journal of Medical Sciences, 2020
Mechanical ventilation (MV) is a common life support system in intensive care units. Accurate identification of patients who are capable of being extubated can shorten the MV duration and potentially reduce MV‐related complications. Therefore, prediction
Wei‐Chan Chung, Chau‐Chyun Sheu, Jen‐Yu Hung, Tuan‐Jung Hsu, Ssu‐Han Yang, Jong‐Rung Tsai   +5 more
doaj   +1 more source

Immune System Development—Pro Tips for Paediatricians

Acta Paediatrica, EarlyView.
ABSTRACT There are many misconceptions about the immune system in children, its impact on infectious disease susceptibility and its role in the rapidly increasing rates of immune mediated diseases in industrialized societies. In this mini review, I will discuss common believes and the data supporting or countering such believes, with a focus on ...
Petter Brodin
wiley   +1 more source

Effect of post-weaning management practices on physiological and immunological responses of weaned beef calves [PDF]

, 2011
peer-reviewedThe objectives were: i) to investigate the physiological and immunological responses of previously grazed, abruptly weaned beef calves that were then either housed (H) and offered a diet of grass silage ad libitum plus concentrate or ...
Lynch, E.M., McGee, Mark, McGee, M., Lynch, Eilish M, Doyle, Sean, Earley, Bernadette, Earley, B.   +6 more
core   +1 more source

Application of Modified Ventilator Bundle and Its Effect on Weaning and Ventilation Days among Critical Ill Patients

Evidence-Based Nursing Research
Context: Modified ventilator bundle is the group of interventions supported by evidence to prevent ventilator-associated pneumonia and other related complications that commonly occurred in mechanically ventilated patients.
Amany S. Eweas, Sahar Y. Mohammad, Jehan S. A. Sayyed, Marwa M. Abd Elbaky, Magda M. Bayoumi   +4 more
doaj   +1 more source

Monitoring diaphragm function in a patient with myasthenia gravis: electrical activity of the diaphragm vs. maximal inspiratory pressure

Journal of Intensive Care, 2017
Background Maximal inspiratory pressure (MIP) is used to assess respiratory muscle strength of patients with myasthenia gravis (MG) requiring ventilatory support. Electrical activity of the diaphragm (E-di) has been used to guide weaning.
Yukiko Koyama, Takeshi Yoshida, Akinori Uchiyama, Yuji Fujino   +3 more
doaj   +1 more source

Decoding neuronal vulnerability: Multidimensional analysis of D1R‐ and D2R‐ medium‐sized spiny neurons in Huntington's disease

Brain Pathology, EarlyView.
D1R and D2R MSNs show distinct responses to Huntington's pathology. G&T‐sequencing of pre‐symptomatic MSNs reveals global LINE‐1 downregulation. While D1R‐MSNs display early transcriptomic changes (OXPHOS/translation upregulation) and reduced mutant huntingtin aggregation, D2R‐MSNs exhibit higher nuclear mHTT accumulation and greater CAG somatic ...
Guendalina Bergonzoni, Miguel Pellegrini, Aurora Savino, Martina Lazioli, Sarah Geurs, Lorenzo Graziani, Denise Ferrarini, Solaleh Khoramian Tusi, Esaria Oliver, Jarne Geurts, Sara Vinciguerra, Michele Tebaldi, Takshashila Tripathi, Isabella Pesce, Valeria Poli, Alessandro Romanel, Rosario Moratalla, Thierry Voet, Jasmin Morandell, Remo Sanges, Vanessa C. Wheeler, Erik Dassi, Marta Biagioli   +22 more
wiley   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

Progressive Pulmonary Alveolar Proteinosis Diagnosis Masking Pneumonic Lung Carcinoma: Anchoring Bias in Critical Care

Cytopathology, EarlyView.
A presumed case of pulmonary alveolar proteinosis with clinical deterioration was ultimately identified at autopsy as pneumonic‐type pleomorphic carcinoma. This case highlights the diagnostic overlap between diffuse lung diseases and the risk of anchoring bias in critically ill patients.
Dakota Wheeler, Rhaya Murray, Teklu Legesse, Hector Mesa   +3 more
wiley   +1 more source