Results 181 to 190 of about 14,797 (308)

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li   +11 more
wiley   +1 more source

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang   +12 more
wiley   +1 more source

Experiences and perceptions of non-intensive care trained nurses in caring for patients on mechanical ventilators in Mahalapye district hospital, Botswana.

open access: yes
Thesis of Master of Science in Critical Care Nursing.There is increasing patient acuity in Intensive Care Units (ICUs) in Botswana, with a growing demand for mechanical ventilation. As a result, non-intensive care-trained nurses are increasingly involved
Bohutsana, Gabarate
core  

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

open access: yesAnnals of Neurology, EarlyView.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones   +54 more
wiley   +1 more source

Tracheostomy timing and weaning outcomes following prolonged mechanical ventilation. [PDF]

open access: yesBMC Pulm Med
Ghiani A   +5 more
europepmc   +1 more source

Research on Evaporation Characteristics and Safe Storage Duration of Marine Liquid Hydrogen Storage Tanks Under the Coupling Effect of Heat Leakage and Sloshing

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Liquid hydrogen, a zero‐carbon and high–energy‐density fuel, is a promising option for future oceangoing vessels. During maritime transportation, onboard cryogenic tanks are exposed to ambient heat leakage and ship‐induced roll motion, which can trigger sloshing and fundamentally modify the coupled thermo‐fluid processes governing boil‐off and
Yan Deng   +5 more
wiley   +1 more source

Outcomes of children after initiation of home mechanical ventilation via tracheostomy: a single center retrospective study. [PDF]

open access: yesBMC Pulm Med
Kreger JE   +6 more
europepmc   +1 more source

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