Results 51 to 60 of about 104,006 (269)
Ventral striatum’s role in learning from gains and losses [PDF]
Proceedings of the National Academy of Sciences, 2018 Significance A broad set of neural circuits, including the amygdala and frontal-striatal systems, has been implicated in mediating learning from gains and losses. The ventral striatum (VS) has been implicated in several aspects of this process. Here, we examined the specific contribution of the VS to learning from gains vs. losses.
Craig A. Taswell +3 more
openaire +2 more sources
Opposing amygdala and ventral striatum connectivity during emotion identification [PDF]
Brain and Cognition, 2011 Lesion and electrophysiological studies in animals provide evidence of opposing functions for subcortical nuclei such as the amygdala and ventral striatum, but the implications of these findings for emotion identification in humans remain poorly described.
Theodore D, Satterthwaite +10 more
openaire +2 more sources
Neural signatures of cognitive flexibility and reward sensitivity following nicotinic receptor stimulation in dependent smokers : a randomized trial [PDF]
, 2017 IMPORTANCE Withdrawal from nicotine is an important contributor to smoking relapse. Understanding how reward-based decision making is affected by abstinence and by pharmacotherapies such as nicotine replacement therapy and varenicline tartrate may aid ...
Aronson, Sarah E. +5 more
core +2 more sources
The Neural Mechanisms Underlying the Influence of Pavlovian Cues on Human Decision Making [PDF]
, 2008 In outcome-specific transfer, pavlovian cues that are predictive of specific outcomes bias action choice toward actions associated with those outcomes.
Balleine, Bernard +4 more
core +2 more sources
Frontiers in Neurology, 2018 Background: Around 30% Parkinson's disease (PD) patients develop impulse control disorders (ICDs) to D2/3 dopamine agonists and, to a lesser extent, levodopa.
Alice Martini +5 more
doaj +1 more source
Advanced Science, EarlyView.This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
In vivo evidence of neurophysiological maturation of the human adolescent striatum
Developmental Cognitive Neuroscience, 2015 Maturation of the striatum has been posited to play a primary role in observed increases in adolescent sensation-seeking. However, evidence of neurophysiological maturation in the human adolescent striatum is limited.
Bart Larsen, Beatriz Luna
doaj +1 more source
Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers [PDF]
Developmental Neuropsychology, 2016 Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers.
Jollans, Lee +27 more
openaire +3 more sources
Advanced Science, EarlyView.Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li +13 more
wiley +1 more source
Decreased dopamine activity predicts relapse in methamphetamine abusers. [PDF]
, 2012 Studies in methamphetamine (METH) abusers showed that the decreases in brain dopamine (DA) function might recover with protracted detoxification. However, the extent to which striatal DA function in METH predicts recovery has not been evaluated.
Alia-Klein, N +11 more
core +1 more source