Results 1 to 10 of about 42,639 (223)

Exploratory MIA study: multimodal magnetic resonance imaging characteristics of rat offspring induced by maternal Poly(I:C) exposure during pregnancy [PDF]

open access: yesFrontiers in Psychiatry
BackgroundMaternal infection or inflammatory stimulation during pregnancy can disrupt fetal brain development through immune activation, increasing the risk of psychiatric disorders in offspring, including schizophrenia.
Bin Wu   +4 more
doaj   +2 more sources

Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): Ecstasy is a popular recreational psychostimulant with side effects on the central nervous system. This study examined the corpus striatum tissue of adult rats that received ecstasy during the embryonic period for histological and molecular
Zahra Nazari   +2 more
doaj   +1 more source

A Multivariate Surface-Based Analysis of the Putamen in Premature Newborns: Regional Differences within the Ventral Striatum [PDF]

open access: yes, 2013
Many children born preterm exhibit frontal executive dysfunction, behavioral problems including attentional deficit/hyperactivity disorder and attention related learning disabilities.
An, X   +9 more
core   +8 more sources

Long-segment common carotid occlusion presenting with limb-shaking transient ischemic attack: Case report

open access: yesFrontiers in Surgery, 2023
BackgroundLimb-shaking transient ischemic attack (LS-TIA) is a rare manifestation of carotid artery occlusion. Common carotid artery occlusion (CCAO) is a relatively rare condition, and both its natural history and recommendations for treatment are still
Qingjun Jiang   +4 more
doaj   +1 more source

Obesity Associated Cerebral Gray and White Matter Alterations Are Interrelated in the Female Brain. [PDF]

open access: yesPLoS ONE, 2014
Obesity is known to affect the brain's gray matter (GM) and white matter (WM) structure but the interrelationship of such changes remains unclear. Here we used T1-weighted magnetic resonance imaging (MRI) in combination with voxel-based morphometry (VBM)
Karsten Mueller   +7 more
doaj   +1 more source

A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2

open access: yesStem Cell Research, 2020
GSX2 is a homeobox transcription factor (TF) controlling the specification of the ventral lateral ganglionic eminence and its major derivative, the corpus striatum. Medium spiny neurons (MSNs) represent the largest cell component of the striatum and they
Dario Besusso   +8 more
doaj   +1 more source

Glutamate (mGluR-5) gene expression in brain regions of streptozotocin induced diabetic rats as a function of age: role in regulation of calcium release from the pancreatic islets in vitro

open access: yesJournal of Biomedical Science, 2009
Metabotrophic glutamate receptors (mGluRs) modulate cellular activities involved in the processes of differentiation and degeneration. In this study, we have analysed the expression pattern of group-I metabotropic glutamate receptor (mGlu-5) in cerebral ...
Paulose CS   +2 more
doaj   +1 more source

Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. [PDF]

open access: yes, 2015
BackgroundMultiple system atrophy (MSA) is a neurodegenerative disease characterized by parkinsonism, ataxia and dysautonomia. Histopathologically, the hallmark of MSA is the abnormal accumulation of alpha-synuclein (α-syn) within oligodendroglial cells,
Adame, Anthony   +12 more
core   +2 more sources

The Differentially Expressed Circular RNAs in the Substantia Nigra and Corpus Striatum of Nrf2-Knockout Mice

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway plays a protective role in both acute neuronal damage and chronic neurodegeneration-related oxidative stress.
Jun-Hui Yang   +7 more
doaj   +1 more source

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