Results 1 to 10 of about 27,257 (160)

Mapping brain volume changes in the zQ175DN mouse model of Huntington’s disease: a longitudinal MRI study [PDF]

Biomarker Research
Background Huntington’s disease (HD) is a progressive neurodegenerative disease affecting motor and cognitive abilities, as well as exhibiting psychiatric manifestations.
Nicholas Vidas-Guscic, Tamara Vasilkovska, Stefanie Pluym, Joëlle van Rijswijk, Johan Van Audekerke, Haiying Tang, Ignacio Muñoz-Sanjuán, Dorian Pustina, Roger Cachope, Annemie Van der Linden, Daniele Bertoglio, Marleen Verhoye   +11 more
doaj   +2 more sources

Morphometric Brain Changes in a Merino Sheep (Ovis aries) CLN6 Neuronal Ceroid Lipofuscinosis Model [PDF]

Biology
The neuronal ceroid lipofuscinoses are the most common group of human paediatric genetic neurodegenerative disorders and have also been reported in multiple animal species.
Amelia Nanni, Emma Elcombe, Maverick Ho Ming Cheung, Timothy Stait-Gardner, Marina Gimeno, Imke Tammen, Marianne D. Keller   +6 more
doaj   +2 more sources

AN EXPERIMENTAL RESEARCH INTO THE ANATOMY AND PHYSIOLOGY OF THE CORPUS STRIATUM [PDF]

Brain, 1914
n ...
S A Kinnier Wilson
exaly   +2 more sources

Effect of MDMA exposure during pregnancy on cell apoptosis, astroglia, and microglia activity in rat offspring striatum [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Ecstasy is a popular recreational psychostimulant with side effects on the central nervous system. This study examined the corpus striatum tissue of adult rats that received ecstasy during the embryonic period for histological and molecular
Zahra Nazari, Khadijeh Bahrebar, Mohammad Jafar Golalipour   +2 more
doaj   +1 more source

Long-segment common carotid occlusion presenting with limb-shaking transient ischemic attack: Case report

Frontiers in Surgery, 2023
BackgroundLimb-shaking transient ischemic attack (LS-TIA) is a rare manifestation of carotid artery occlusion. Common carotid artery occlusion (CCAO) is a relatively rare condition, and both its natural history and recommendations for treatment are still
Qingjun Jiang, Jun Bai, Shaojie Nie, Jie Jin, Lefeng Qu   +4 more
doaj   +1 more source

Obesity Associated Cerebral Gray and White Matter Alterations Are Interrelated in the Female Brain. [PDF]

PLoS ONE, 2014
Obesity is known to affect the brain's gray matter (GM) and white matter (WM) structure but the interrelationship of such changes remains unclear. Here we used T1-weighted magnetic resonance imaging (MRI) in combination with voxel-based morphometry (VBM)
Karsten Mueller, Annette Horstmann, Harald E Möller, Alfred Anwander, Jöran Lepsien, Matthias L Schroeter, Arno Villringer, Burkhard Pleger   +7 more
doaj   +1 more source

Glutamate (mGluR-5) gene expression in brain regions of streptozotocin induced diabetic rats as a function of age: role in regulation of calcium release from the pancreatic islets in vitro

Journal of Biomedical Science, 2009
Metabotrophic glutamate receptors (mGluRs) modulate cellular activities involved in the processes of differentiation and degeneration. In this study, we have analysed the expression pattern of group-I metabotropic glutamate receptor (mGlu-5) in cerebral ...
Paulose CS, Kumar T Peeyush, Balakrishnan Savitha   +2 more
doaj   +1 more source

A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2

Stem Cell Research, 2020
GSX2 is a homeobox transcription factor (TF) controlling the specification of the ventral lateral ganglionic eminence and its major derivative, the corpus striatum. Medium spiny neurons (MSNs) represent the largest cell component of the striatum and they
Dario Besusso, Andrea Cossu, Ayat Mohamed, Manuel Cernigoj, Paolo Codega, Maura Galimberti, Ilaria Campus, Paola Conforti, Elena Cattaneo   +8 more
doaj   +1 more source

The Differentially Expressed Circular RNAs in the Substantia Nigra and Corpus Striatum of Nrf2-Knockout Mice

Cellular Physiology and Biochemistry, 2018
Background/Aims: The nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) pathway plays a protective role in both acute neuronal damage and chronic neurodegeneration-related oxidative stress.
Jun-Hui Yang, Run-Jiao Zhang, Jia-Jie Lin, Ming-Chao Cao, Qie Wang, Hui-Xian Cui, Shao-Guang Sun, Lei Wang   +7 more
doaj   +1 more source

Enhanced muscarinic M1 receptor gene expression in the corpus striatum of streptozotocin-induced diabetic rats

Journal of Biomedical Science, 2009
Acetylcholine (ACh), the first neurotransmitter to be identified, regulate the activities of central and peripheral functions through interactions with muscarinic receptors. Changes in muscarinic acetylcholine receptor (mAChR) have been implicated in the
Mathew Jobin, Kumar T Peeyush, Gireesh G, Paulose CS   +3 more
doaj   +1 more source