Results 31 to 40 of about 26,636 (182)
Advanced Science, EarlyView.LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan +29 more
wiley +1 more source
Visualization of spatiotemporal dynamics of human glioma stem cell invasion
Molecular Brain, 2019 Glioblastoma exhibits phenotypic and genetic heterogeneity, aggressive invasiveness, therapeutic resistance, and tumor recurrence, which can be explained by the existence of glioma stem cells (GSCs).
Ryota Tamura +14 more
doaj +1 more source
Effect of treadmill exercise on catalepsy and the expression of the BDNF gene in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine male NMRI mice [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): It is known that treadmill exercise has beneficial effects on the nervous system. The brain-derived neurotrophic factor (BDNF) plays a role in such effects.
Neda Nikokalam Nazif +4 more
doaj +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu +7 more
wiley +1 more source
Progressive obtundation in a young woman with bilateral corpus striatum infarction: a case report
Journal of Medical Case Reports, 2011 Background Bilateral ischemic infarction involving the corpus striatum is a rare event which usually results from global cerebral hypoxia, intoxications, and drug abuse.
Zangana Hero M +3 more
doaj +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Epilepsia Open, EarlyView.Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
Oligodendrogenesis after Cerebral Ischemia
Frontiers in Cellular Neuroscience, 2013 Neural stem cells in the subventricular zone (SVZ) of the lateral ventricle of adult rodent brain generate oligodendrocyte progenitor cells (OPCs) that disperse throughout the corpus callosum and striatum where some of OPCs differentiate into mature ...
Ruilan eZhang +3 more
doaj +1 more source
Validation of Optimum ROI Size for 123I-FP-CIT SPECT Imaging Using a 3D Mathematical Cylinder Phantom [PDF]
Asia Oceania Journal of Nuclear Medicine and Biology, 2018 Objective(s): The partial volume effect (PVE) of single-photon emission computedtomography (SPECT) on corpus striatum imaging is caused by the underestimation ofspecific binding ratio (SBR).
Hideo Onishi +3 more
doaj +1 more source
Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li +10 more
wiley +1 more source
HEMIBALLISMUS-HEMICHOREA IN A 55 YEARS OLD DIABETIC FEMALE PATIENT WITH NON-KETOTIC HYPERGLYCAEMIA
Pakistan Armed Forces Medical Journal, 2011 Hemiballismus-hemichorea (HC-BC) are involuntary rapid irregular jerks, invariably unilateral and affect the arms more frequently than legs1. The causative lesion is commonly found in the corpus striatum, but can occur anywhere along the afferent or ...
Abdul Latif Khattak +3 more
doaj +2 more sources