Results 31 to 40 of about 1,039,827 (235)

Ultrastructural Characteristics of Neuronal Death and White Matter Injury in Mouse Brain Tissues After Intracerebral Hemorrhage: Coexistence of Ferroptosis, Autophagy, and Necrosis

Frontiers in Neurology, 2018
Although intracerebral hemorrhage (ICH) is a devastating disease worldwide, the pathologic changes in ultrastructure during the acute and chronic phases of ICH are poorly described.
Qian Li, Qian Li, Qian Li, Abigail Weiland, Xuemei Chen, Xi Lan, Xiaoning Han, Frederick Durham, Xi Liu, Jieru Wan, Wendy C. Ziai, Wendy C. Ziai, Daniel F. Hanley, Jian Wang   +13 more
doaj   +1 more source

Note on the Arteries of the Corpus Striatum [PDF]

The Boston Medical and Surgical Journal, 1907
n ...
Ayer, James B., Aitken, H. F.
openaire   +2 more sources

Studie über die Function des Corpus striatum

, 1886
STUDIE ÜBER DIE FUNCTION DES CORPUS STRIATUM Full title: Archiv für Anatomie und Physiologie. Physiologische Abteilung, Archiv für Physiologie (-) Archiv für Physiologie (-) Studie über die Function des Corpus striatum (-
Lehmann, Curt Adolf Baginsky
core   +2 more sources

Connectivity Alterations in Vascular Parkinsonism: A Structural Covariance Study

Applied Sciences, 2022
This study aimed to investigate the structural covariance between the striatum and large-scale brain regions in patients with vascular parkinsonism (VP) compared to Parkinson’s disease (PD) and control subjects, and then explore the relationship between ...
Fabiana Novellino, Maria Salsone, Roberta Riccelli, Carmelina Chiriaco, Giuseppe Argirò, Andrea Quattrone, José L. M. Madrigal, Luigi Ferini Strambi, Aldo Quattrone   +8 more
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

THE HISTOPATHOLOGIC EFFECT OF SHORT-TERM ADMINISTRATION OF HALOPERIDOL ON RABBIT STRIATUM

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Studies related to mechanism of action of antipsychotic drugs are being gone on and still some studies are carried out whether these drugs might lead to structural changes in brain and whether these changes might be associated with ...
Nazan Aydın, Mehmet Dumlu Aydın, Ali Çayköylü, Cemal Gündoğdu, Fazlı Erdoğan   +4 more
doaj  

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Golgi Protein ACBD3 Mediates Neurotoxicity Associated with Huntington’s Disease

Cell Reports, 2013
Huntington’s disease (HD) is an autosomal-dominant neurodegenerative disease caused by the expansion of polyglutamine repeats in the gene for huntingtin (Htt).
Juan I. Sbodio, Bindu D. Paul, Carolyn E. Machamer, Solomon H. Snyder   +3 more
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source