Results 51 to 60 of about 26,636 (182)

17 Β-Estradiol Oxidative Stress Attenuation And Autophagy-Induced Dopaminergic Neuroprotection

Cell Journal, 2018
Objective Degeneration of dopaminergic neurons in the substantia nigra of the brain stem is the main pathological aspect of Parkinson’s disease (PD). 17 β-estradiol (E2) has neuroprotective effects on substantia nigra, however, the underlined mechanism ...
Roya Varmazyar, Ali Noori-Zadeh, Farzad Rajaei, Shahram Darabi, Salar Bakhtiyari   +4 more
doaj   +1 more source

Longitudinal MRI studies of children with attention‐deficit/hyperactivity disorder: A systematic review

Psychiatry and Clinical Neurosciences, EarlyView.
We reviewed longitudinal magnetic resonance imaging (MRI) studies exploring the brain development of children with attention‐deficit/hyperactivity disorder (ADHD). Specifically, we conducted a systematic review of papers published until 9 September 2025 in English on pediatric patients with ADHD.
Ayaka Ishii‐Takahashi, Yuzu Yoshimaru, Dwi Muhammad, Takuya Kawahara, Rio Yamaguchi   +4 more
wiley   +1 more source

Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo

Frontiers in Molecular Neuroscience, 2020
Neuroinflammation is an important factor in the pathogenesis of neurodegenerative diseases. Microglia-derived lysosomal cathepsins have been increasingly recognized as important inflammatory mediators that trigger signaling pathways that aggravate ...
Anja Pišlar, Larisa Tratnjek, Larisa Tratnjek, Gordana Glavan, Nace Zidar, Marko Živin, Janko Kos, Janko Kos   +7 more
doaj   +1 more source

Finding the Words: How Does the Aging Brain Process Language? A Focused Review of Brain Connectivity and Compensatory Pathways

Topics in Cognitive Science, EarlyView.
Abstract As people age, there is a natural decline in cognitive functioning and brain structure. However, the relationship between brain function and cognition in older adults is neither straightforward nor uniform. Instead, it is complex, influenced by multiple factors, and can vary considerably from one person to another.
Monica Baciu, Elise Roger
wiley   +1 more source

Lower cerebral blood flow but not cerebrovascular response in elastin haploinsufficient mice

Experimental Physiology, EarlyView.
Abstract Elastin insufficiency is associated with structural differences in the large elastic arteries and cerebral artery dysfunction. However, previous studies have not assessed potential sex differences in cerebrovascular function. We measured cerebral blood flow (CBF) using arterial spin labeling MRI at rest and in response to hypercapnia challenge
Abigail E. Cullen, Emily H. Reeve, Nick R. Winder, Grant D. Henson, Nayantara Arora, Thomas Leonhardt, Ainsley Hogan, Sahana Krishna Kumaran, Naly Setthavonsack, Victoria Krajbich, Art Riddle, Benjamin Zimmerman, Nabil J. Alkayed, Martin M. Pike, Randall L. Woltjer, Ashley E. Walker   +15 more
wiley   +1 more source

Increased Binding of [18F]Nifene, a PET Imaging Probe for α4β2* Nicotinic Acetylcholinergic Receptors in Hippocampus–Subiculum of Postmortem Human Parkinson's Disease Brain

Synapse, Volume 80, Issue 5, September 2026.
[18F]Nifene, a PET imaging probe for α4β2* nicotinic acetylcholine receptors, was used to discretely measure changes in hippocampus (HP) and subiculum (SUB) of postmortem Parkinson's disease (PD) cases compared to cognitively normal (CN) cases. Significant increased [18F]nifene binding in PD was observed.
Jogeshwar Mukherjee, Fariha Karim, Allyson Ngo, Christopher Liang, Geidy E. Serrano, Thomas G. Beach   +5 more
wiley   +1 more source

30- and 60-days exposure of sodium fluoride induces neurobehavioral deficits and alters neurochemical parameters in adult Wistar rats

Discover Toxicology
Objective Exposure to fluoride above the recommended dose has been shown to have toxicological consequences on several body systems. There is a paucity of information on neurotoxic effect of exposure of varying doses of sodium fluoride (NaF) on specific ...
Ademola Adetokunbo Oyagbemi, Ifeoluwa Awogbindin, Ebenezer Oyedele Ajiboye, Yusuf Ekundayo Mustapha, Fatimah Salami-Ayodeji, Omowumi Moromoke Femi-Akinlosotu, Adedunsola Adewunmi Obasa, Oluwabusayo Racheal Folarin, Temitayo Olabisi Ajibade, Olumayowa Olawumi Igado, Adeola Temitope Salami, Oluwaseun Olanrewaju Esan, Taiwo Olaide Oyagbemi, Adewunmi Victoria Adeogun, Ishmael Festus Jaja, Olufunke Eunice Ola-Davies, Temidayo Olutayo Omobowale, Adebowale Bernard Saba, James Olukayode Olopade, Sanah Malomile Nkadimeng, Lyndy Joy McGaw, Prudence Ngalula Kayoka-Kabongo, Oluwafemi Omoniyi Oguntibeju, Momoh Audu Yakubu   +23 more
doaj   +1 more source

Pickleball Tremor

Movement Disorders Clinical Practice, EarlyView.
Joseph Jankovic
wiley   +1 more source

Lower Striatal and Cortical Calretinin Interneuron Density Associated With Altered Social Behavior in Cntnap2 Knockout Mice

Autism Research, Volume 19, Issue 7, July 2026.
ABSTRACT Variants in the CNTNAP2 gene, encoding the cell adhesion molecule CASPR2, have been identified as genetic risk factors for autism spectrum disorder (ASD). However, the mechanisms through which CNTNAP2 dysfunction alters circuit function remain unknown.
Krisztina Sáfár, Vivien Szendi, Paulina Hoppa, Yutong Wang, Fanni Á. Seres, Szilvia Bartók, Tyler Teadora, Lei Shi, Árpád Dobolyi, Gina Puska, István Adorján   +10 more
wiley   +1 more source

Study on microstructure of corpus striatum in patients with idiopathic rapid eye movement sleep behavior disorder using magnetic resonance imaging

Chinese Journal of Contemporary Neurology and Neurosurgery, 2017
Objective To investigate the structure of corpus striatum and the integrity of white matter fiber in patients with Parkinson's disease (PD) and idiopathic rapid eye movement sleep behavior disorder (iRBD).
Ya-meng ZHANG, Hong-li WANG, Ying-ying BAI, Wen-jie HE, Yang YOU, Hong-ju ZHANG, Jie-wen ZHANG   +6 more
doaj