Results 71 to 80 of about 42,639 (223)
Brain 3-Mercaptopyruvate Sulfurtransferase (3MST): Cellular Localization and Downregulation after Acute Stroke. [PDF]
PLoS ONE, 2013 3-Mercaptopyruvate sulfurtransferase (3MST) is an important enzyme for the synthesis of hydrogen sulfide (H2S) in the brain. We present here data that indicate an exclusively localization of 3MST in astrocytes. Regional distribution of 3MST activities is
Heng Zhao +3 more
doaj +1 more source
The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]
, 1992 Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F +3 more
core +1 more source
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To evaluate Frequency Alternation at Low duty cycle for Single Offset (FALSO) as a novel Magnetization Transfer (MT) preparation scheme to increase speed and/or spatial resolution of inhomogeneous MT (ihMT) MRI by reducing the number of volumes required.
Gopal Varma +5 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang +7 more
wiley +2 more sources
17 Β-Estradiol Oxidative Stress Attenuation And Autophagy-Induced Dopaminergic Neuroprotection
Cell Journal, 2018 Objective Degeneration of dopaminergic neurons in the substantia nigra of the brain stem is the main pathological aspect of Parkinson’s disease (PD). 17 β-estradiol (E2) has neuroprotective effects on substantia nigra, however, the underlined mechanism ...
Roya Varmazyar +4 more
doaj +1 more source
CUL3‐Related Neurodevelopmental Disorder: Expanding the Prenatal Phenotype
Prenatal Diagnosis, EarlyView.ABSTRACT Objective Pathogenic variants of the CUL3 gene are known to cause a neurodevelopmental disorder with a partially described prenatal phenotype. This study further characterizes and expands the spectrum of prenatal sonographic findings associated with the disorder to improve prenatal diagnosis and counseling.
Yoel Gofin +12 more
wiley +1 more source
Evolution of extra-nigral damage predicts behavioural deficits in a rat proteasome inhibitor model of Parkinson's disease. [PDF]
PLoS ONE, 2011 Establishing the neurological basis of behavioural dysfunction is key to provide a better understanding of Parkinson's disease (PD) and facilitate development of effective novel therapies. For this, the relationships between longitudinal structural brain
Anthony C Vernon +3 more
doaj +1 more source
Time course of oxidative damage in different brain regions following transient cerebral ischemia in gerbils [PDF]
, 2001 The time course of oxidative damage in different brain regions was investigated in the gerbil model of transient cerebral ischemia. Animals were subjected to both common carotid arteries occlusion for 5 min.
Al-Dalain, Saied M. +4 more
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Brain Pathology, EarlyView.Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong +8 more
wiley +1 more source
When Alcoholism Affects Memory Functions: MRI of the Brain. [PDF]
, 1995 The development of modern imaging techniques makes it possible to examine directly the relationship between brain abnormalities and memory impairment.
Jernigan, Terry L, Ostergaard, Arne L
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