An exploratory investigation of brain collateral circulation plasticity after cerebral ischemia in two experimental C57BL/6 mouse models [PDF]
Brain collateral circulation is an essential compensatory mechanism in response to acute brain ischemia. To study the temporal evolution of brain macro and microcollateral recruitment and their reciprocal interactions in response to different ischemic ...
Bentele, Kajetan +14 more
core +1 more source
Pharmacologic MRI Brain Imaging Studies of Serotonin 5‐HT1 Receptor Agonists in Awake Mice
ABSTRACT Serotonin (5‐hydroxytryptamine, 5‐HT) type‐1 G protein‐coupled receptors are expressed throughout the central nervous system. 5‐HT1AR activation is the putative mechanism of approved drugs for generalized anxiety disorder and major depressive disorder and is being studied in the treatment of autism and neurological disorders.
Brittany M. Brems +5 more
wiley +1 more source
This SDM‐PSI meta‐analysis identified consistent regional brain activity alterations in social anxiety disorder, including hyperactivity in the left superior parietal gyrus, right cerebellum, and right supramarginal gyrus, and hypoactivity in the left insula and right supplementary motor area, with age and symptom severity modulating specific regions ...
Sen Li +10 more
wiley +1 more source
Internal carotid artery occlusion associated with Mycoplasma pneumoniae infection in a child
We describe a seven-year-old girl with severe pneumonia probably associated with Mycoplasma pneumoniae who developed right-sided hemiparalysis and right central facial paralysis soon after the onset of the disease.
Gönül Tanir +3 more
doaj
Reward circuitry is perturbed in the absence of the serotonin transporter [PDF]
The serotonin transporter (SERT) modulates the entire serotonergic system in the brain and influences both the dopaminergic and norepinephrinergic systems.
Bearer, Elaine L. +4 more
core +1 more source
Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos +3 more
wiley +1 more source
NEUROPATHOLOGICAL CHANGES IN THE PDAPP TRANSGENIC MOUSE MODEL OF ALZHEIMER’S DISEASE [PDF]
Alzheimer’s disease (AD) is a uniquely human disorder. Although the pathogenesis of AD is not fully understood, growing evidence indicates that the deposition of beta-amyloid (Aβ) and the local reactions of various cell types to this protein play major ...
P. Pasbakhsh +1 more
doaj +1 more source
The third man: Robert Dunn’s (1799-1877) contribution to aphasia research in mid 19th century England [PDF]
Throughout his medical career, Robert Dunn (1799-1877) published a number of clinical cases with post-mortem reports involving acquired language disorders, the first noted in 1842.
Lorch, Marjorie
core +1 more source
ATP-binding cassette (ABC) transporters prevent the access of pharmacological compounds to the ischemic brain, thereby impeding the efficacy of stroke therapies.
Daniel Manrique-Castano +7 more
doaj +1 more source
Iron Deficiency-Induced Changes in the Hippocampus, Corpus Striatum, and Monoamines Levels That Lead to Anxiety, Depression, Sleep Disorders, and Psychotic Disorders. [PDF]
Shah HE +6 more
europepmc +1 more source

