Results 61 to 70 of about 1,039,827 (235)

Machine Learning Prediction of Hoehn and Yahr Scores at 5‐Years Post‐123I‐Ioflupane SPECT Imaging in a Real‐World Parkinson's Disease Dataset

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) progression is highly heterogeneous, complicating clinical management and prognostication. While machine learning models have been developed using research datasets such as Parkinson's Precision Medicine Initiative (PPMI) and Parkinson's Disease Biomarkers Program (PDBP), their clinical translatability is ...
Xuehua Ye, Mette Niemann Johansen, Balazs Laczi, Mads Peter Horndrup, Michael Zaucha Sørensen, Rasmus Vestergård Madsen, Jan Wolber, Markus Lonsdale, Annemette Lokkegaard, Renee Miller   +9 more
wiley   +1 more source

Moxibustion improves motor function by down-regulating SNX5 and inhibiting ferroptosis in neurons of corpus striatum in mice with Parkinson’s disease

针刺研究
ObjectiveTo explore the effect of moxibustion on the expression of sorting nexin 5 （SNX5）， glutathione peroxidase （GPX4） and ferritin heavy chain （FTH1） in the corpus striatum in mice with Parkinson’s disease （PD）， so as to explore its mechanisms ...
GAO Da, LI Qing-lian, WANG Qi-zhang, WU Chun-xiao, HAO Xiao-qian, WANG Xiao-ling, LI Meng-zhu, ZHAO Li-jun, ZHU Mei-ling   +8 more
doaj   +2 more sources

17 Β-Estradiol Oxidative Stress Attenuation And Autophagy-Induced Dopaminergic Neuroprotection

Cell Journal, 2018
Objective Degeneration of dopaminergic neurons in the substantia nigra of the brain stem is the main pathological aspect of Parkinson’s disease (PD). 17 β-estradiol (E2) has neuroprotective effects on substantia nigra, however, the underlined mechanism ...
Roya Varmazyar, Ali Noori-Zadeh, Farzad Rajaei, Shahram Darabi, Salar Bakhtiyari   +4 more
doaj   +1 more source

Annual Research Review: Sex differences in conduct disorder – revisiting existing evidence and exploring future directions

Journal of Child Psychology and Psychiatry, EarlyView.
Conduct disorder (CD) is a common psychiatric disorder in youth, characterized by severe and recurrent aggressive and antisocial behaviors and associated with substantial healthcare and societal costs. Rates of CD increase during adolescence in both sexes, with the male‐to‐female ratio narrowing to approximately 1:1.
Anka Bernhard, Christine M. Freitag, Kerstin Konrad, Lucres Jansen, Andreas G. Chiocchetti, Christina Stadler, Stephane A. De Brito, Graeme Fairchild, Gregor Kohls   +8 more
wiley   +1 more source

Corpus striatum

, 1997
Corpus striatum. Coronal plane.

core  

Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo

Frontiers in Molecular Neuroscience, 2020
Neuroinflammation is an important factor in the pathogenesis of neurodegenerative diseases. Microglia-derived lysosomal cathepsins have been increasingly recognized as important inflammatory mediators that trigger signaling pathways that aggravate ...
Anja Pišlar, Larisa Tratnjek, Larisa Tratnjek, Gordana Glavan, Nace Zidar, Marko Živin, Janko Kos, Janko Kos   +7 more
doaj   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

30- and 60-days exposure of sodium fluoride induces neurobehavioral deficits and alters neurochemical parameters in adult Wistar rats

Discover Toxicology
Objective Exposure to fluoride above the recommended dose has been shown to have toxicological consequences on several body systems. There is a paucity of information on neurotoxic effect of exposure of varying doses of sodium fluoride (NaF) on specific ...
Ademola Adetokunbo Oyagbemi, Ifeoluwa Awogbindin, Ebenezer Oyedele Ajiboye, Yusuf Ekundayo Mustapha, Fatimah Salami-Ayodeji, Omowumi Moromoke Femi-Akinlosotu, Adedunsola Adewunmi Obasa, Oluwabusayo Racheal Folarin, Temitayo Olabisi Ajibade, Olumayowa Olawumi Igado, Adeola Temitope Salami, Oluwaseun Olanrewaju Esan, Taiwo Olaide Oyagbemi, Adewunmi Victoria Adeogun, Ishmael Festus Jaja, Olufunke Eunice Ola-Davies, Temidayo Olutayo Omobowale, Adebowale Bernard Saba, James Olukayode Olopade, Sanah Malomile Nkadimeng, Lyndy Joy McGaw, Prudence Ngalula Kayoka-Kabongo, Oluwafemi Omoniyi Oguntibeju, Momoh Audu Yakubu   +23 more
doaj   +1 more source

Longitudinal MRI studies of children with attention‐deficit/hyperactivity disorder: A systematic review

Psychiatry and Clinical Neurosciences, EarlyView.
We reviewed longitudinal magnetic resonance imaging (MRI) studies exploring the brain development of children with attention‐deficit/hyperactivity disorder (ADHD). Specifically, we conducted a systematic review of papers published until 9 September 2025 in English on pediatric patients with ADHD.
Ayaka Ishii‐Takahashi, Yuzu Yoshimaru, Dwi Muhammad, Takuya Kawahara, Rio Yamaguchi   +4 more
wiley   +1 more source

Study on microstructure of corpus striatum in patients with idiopathic rapid eye movement sleep behavior disorder using magnetic resonance imaging

Chinese Journal of Contemporary Neurology and Neurosurgery, 2017
Objective To investigate the structure of corpus striatum and the integrity of white matter fiber in patients with Parkinson's disease (PD) and idiopathic rapid eye movement sleep behavior disorder (iRBD).
Ya-meng ZHANG, Hong-li WANG, Ying-ying BAI, Wen-jie HE, Yang YOU, Hong-ju ZHANG, Jie-wen ZHANG   +6 more
doaj