The Influence of Striatal Astrocyte Dysfunction on Locomotor Activity in Dopamine-depleted Rats
Basic and Clinical Neuroscience, 2021 Introduction: Astrocyte dysfunction is the common pathology failing astrocyte-neuron interaction in neurological diseases, including Parkinson’s Disease (PD).
Dmitry Voronkov +5 more
doaj
PLoS ONE, 2023 In this study, we investigated the role of glutamate delta 1 receptor (GluD1) in oligodendrocyte progenitor cell (OPC)-mediated myelination during basal (development) and pathophysiological (cuprizone-induced demyelination) conditions.
Sukanya G Gakare +3 more
doaj +1 more source
Semi-automatic parcellation of the corpus striatum [PDF]
SPIE Proceedings, 2007 The striatum is the input component of the basal ganglia from the cerebral cortex. It includes the caudate, putamen, and nucleus accumbens. Thus, the striatum is an important component in limbic frontal-subcortical circuitry and is believed to be relevant both for reward-guided behaviors and for the expression of psychosis.
Ramsey, Al-Hakim +4 more
openaire +2 more sources
Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent [PDF]
, 2009 Decreased rates of transmission of transmissible spongiform encephalopathies (TSEs) to sheep have been attributed to some polymorphisms of the prion protein (PrP) and to a ‘species barrier’ on interspecies experiments.
Card +21 more
core +1 more source
Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease
Antioxidants, 2021 Huntington’s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting ...
Bindu D. Paul
doaj +1 more source
Resuscitation of newborn piglets. short-term influence of FiO2 on matrix metalloproteinases, caspase-3 and BDNF. [PDF]
PLoS ONE, 2010 BACKGROUND: Perinatal hypoxia-ischemia is a major cause of mortality and cerebral morbidity, and using oxygen during newborn resuscitation may further harm the brain.
Rønnaug Solberg +7 more
doaj +1 more source
Orbitofrontal cortex volume and brain reward response in obesity. [PDF]
, 2015 Background/objectivesWhat drives overconsumption of food is poorly understood. Alterations in brain structure and function could contribute to increased food seeking.
Brown, MS +6 more
core +3 more sources
Susceptibility Weighted Imaging as a Useful Imaging Adjunct in Hemichorea Hyperglycaemia
Case Reports in Radiology, 2013 Hyperglycaemia with hemichorea (HGHC) is an unusual clinical entity that can be associated with corpus striatum hyperintensity on T1-weighted (T1W) magnetic resonance imaging (MRI) sequences.
Ferry Dharsono +3 more
doaj +1 more source
Connectivity Alterations in Vascular Parkinsonism: A Structural Covariance Study
Applied Sciences, 2022 This study aimed to investigate the structural covariance between the striatum and large-scale brain regions in patients with vascular parkinsonism (VP) compared to Parkinson’s disease (PD) and control subjects, and then explore the relationship between ...
Fabiana Novellino +8 more
doaj +1 more source
Dopamine D_2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive 4 nicotinic receptors via a cholinergic-dependent mechanism [PDF]
, 2010 Recent studies suggest that high-affinity neuronal nicotinic acetylcholine receptors (nAChRs) containing α4 and β2 subunits (α4β2*) functionally interact with G-protein-coupled dopamine (DA) D_2 receptors in basal ganglia.
Andrew R. Tapper +18 more
core +3 more sources