Results 21 to 30 of about 1,039,827 (235)

Decoding neuronal vulnerability: Multidimensional analysis of D1R- and D2R- medium-sized spiny neurons in Huntington's disease. [PDF]

Brain Pathol
D1R and D2R MSNs show distinct responses to Huntington's pathology. G&T‐sequencing of pre‐symptomatic MSNs reveals global LINE‐1 downregulation. While D1R‐MSNs display early transcriptomic changes (OXPHOS/translation upregulation) and reduced mutant huntingtin aggregation, D2R‐MSNs exhibit higher nuclear mHTT accumulation and greater CAG somatic ...
Bergonzoni G, Pellegrini M, Savino A, Lazioli M, Geurs S, Graziani L, Ferrarini D, Tusi SK, Oliver E, Geurts J, Vinciguerra S, Tebaldi M, Tripathi T, Pesce I, Poli V, Romanel A, Moratalla R, Voet T, Morandell J, Sanges R, Wheeler VC, Dassi E, Biagioli M.   +22 more
europepmc   +2 more sources

Glutamate delta-1 receptor regulates oligodendrocyte progenitor cell differentiation and myelination in normal and demyelinating conditions.

PLoS ONE, 2023
In this study, we investigated the role of glutamate delta 1 receptor (GluD1) in oligodendrocyte progenitor cell (OPC)-mediated myelination during basal (development) and pathophysiological (cuprizone-induced demyelination) conditions.
Sukanya G Gakare, Jay M Bhatt, Kishore Kumar S Narasimhan, Shashank M Dravid   +3 more
doaj   +1 more source

Corpus: CONVERSATIONS LYON SAXE (LSG35): EXTRAIT LSG 35: BISCUIT BUSINESS

, 2018
Interactions entre associés d'une entreprise de consulting en contexte privé (domicile). 3 locuteurs. En orthographe adaptée, Toilettée, Minutée, Anonymisée. La convention de transcription est accessible dans CLAPI.
Balthasar, Lukas, Mondada, Lorenza, Corpus de LAngue Parlée en Interaction, Interactions, Corpus, Apprentissage, Représentations   +3 more
core   +1 more source

Signaling Overlap between the Golgi Stress Response and Cysteine Metabolism in Huntington’s Disease

Antioxidants, 2021
Huntington’s disease (HD) is caused by expansion of polyglutamine repeats in the protein huntingtin, which affects the corpus striatum of the brain. The polyglutamine repeats in mutant huntingtin cause its aggregation and elicit toxicity by affecting ...
Bindu D. Paul
doaj   +1 more source

Corpus: CONVERSATIONS LYON SAXE (LSG35): EXTRAIT LSG 35: BISCUIT BUSINESS

, 2015
Interactions entre associés d'une entreprise de consulting en contexte privé (domicile). Enregistré le 13 juillet 2004 au domicile de Jean-Baptiste. Enregistrement multiscope.
Balthasar, Lukas, Mondada, Lorenza, Corpus de LAngue Parlée en Interaction, Interactions, Corpus, Apprentissage, Représentations   +3 more
core   +1 more source

Delayed-onset parkinsonism is common after isolated striatal infarcts

Frontiers in Neurology
BackgroundWhile case studies have suggested that only a minority of patients with putaminal lesions develop parkinsonism, existing data are limited by involvement of adjacent brain regions, brief follow-up period, and lack of systematic imaging.
Hedda Holm, Hedda Holm, Espen Dietrichs, Espen Dietrichs, Juho Joutsa, Juho Joutsa, James P. Connelly, Christian G. Lund, Mona Skjelland, Mona Skjelland, Vidar Gundersen, Silje Bjerknes   +11 more
doaj   +1 more source

Resuscitation of newborn piglets. short-term influence of FiO2 on matrix metalloproteinases, caspase-3 and BDNF. [PDF]

PLoS ONE, 2010
BACKGROUND: Perinatal hypoxia-ischemia is a major cause of mortality and cerebral morbidity, and using oxygen during newborn resuscitation may further harm the brain.
Rønnaug Solberg, Else Marit Løberg, Jannicke H Andresen, Marianne S Wright, Eliane Charrat, Michel Khrestchatisky, Santiago Rivera, Ola Didrik Saugstad   +7 more
doaj   +1 more source

THE MORPHOLOGY AND FUNCTIONS OF THE CORPUS STRIATUM [PDF]

The Journal of Nervous and Mental Disease, 1915
n ...
openaire   +2 more sources

Susceptibility Weighted Imaging as a Useful Imaging Adjunct in Hemichorea Hyperglycaemia

Case Reports in Radiology, 2013
Hyperglycaemia with hemichorea (HGHC) is an unusual clinical entity that can be associated with corpus striatum hyperintensity on T1-weighted (T1W) magnetic resonance imaging (MRI) sequences.
Ferry Dharsono, Andrew Thompson, Jolandi van Heerden, Andrew Cheung   +3 more
doaj   +1 more source

Corpus Bielefeld, Situation de contact, Tandem, RDA

, 2010
Interactions privéesInteractions construites, interactions en institutionInteractions entre étudiantes sur les différences entre Allemagne et France">Le corpus a été constitué lors d’un projet « tandem » mené dans le cadre d’un séminaire universitaire à ...
Krafft, Ulrich, Dausendschön-Gay, Ulrich, Gülich, Elisabeth, Corpus de LAngue Parlée en Interaction   +3 more
core   +1 more source