Results 71 to 80 of about 576,684 (304)

A coupled mitral valve -- left ventricle model with fluid-structure interaction

open access: yes, 2017
Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to ...
Brown, André EX   +11 more
core   +3 more sources

Moving Domain Computational Fluid Dynamics to Interface with an Embryonic Model of Cardiac Morphogenesis [PDF]

open access: yes, 2013
Peristaltic contraction of the embryonic heart tube produces time- and spatial-varying wall shear stress (WSS) and pressure gradients (∇P) across the atrioventricular (AV) canal.
Beebe, Tyler   +11 more
core   +7 more sources

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

open access: yesArthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim   +18 more
wiley   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

open access: yesAdvanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er   +8 more
wiley   +1 more source

Abnormal calcium homeostasis in heart failure with preserved ejection fraction is related to both reduced contractile function and incomplete relaxation: An electromechanically detailed biophysical modelling study

open access: yesFrontiers in Physiology, 2015
Heart failure with preserved ejection fraction (HFpEF) accounts for about 50% of heart failure cases. It has features of incomplete relaxation and increased stiffness of the left ventricle.
Ismail eAdeniran   +6 more
doaj   +1 more source

Heart-like fair queuing algorithms (HLFQA) [PDF]

open access: yes, 2006
We propose a new family of fair, work conserving traffic scheduling mechanisms that imitate the behavior of the human heart in the cardiovascular system.
Collier, Martin, Dragos, Radu-Calin
core   +1 more source

Calcium Imparts Advanced Functionalities to Silk Hydrogels for Biofabrication and Biomedical Innovation

open access: yesAdvanced Functional Materials, EarlyView.
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran   +11 more
wiley   +1 more source

Segmentation of brain magnetic resonance images based on multi-atlas likelihood fusion: testing using data with a broad range of anatomical and photometric profiles

open access: yesFrontiers in Neuroscience, 2015
We propose a hierarchical pipeline for skull-stripping and segmentation of anatomical structures of interest from T1-weighted images of the human brain. The pipeline is constructed based on a two-level Bayesian parameter estimation algorithm called multi-
Xiaoying eTang   +13 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Automatic segmentation of the left ventricle cavity and myocardium in MRI data [PDF]

open access: yes, 2006
A novel approach for the automatic segmentation has been developed to extract the epi-cardium and endo-cardium boundaries of the left ventricle (lv) of the heart. The developed segmentation scheme takes multi-slice and multi-phase magnetic resonance (MR)
Azhari   +42 more
core   +1 more source

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