Results 51 to 60 of about 165,166 (258)

Pattern of initiation of monomorphic ventricular tachycardia in recorded intracardiac electrograms [PDF]

, 2005
Background: By analyzing stored intracardiac electrograms during spontaneous monomorphic ventricular tachycardia (VT), we examined the patterns of the VT initiation in a group of patients with implantable cardioverter defibrillators (ICDs).
Arya, Arash, Haghjoo, Majid, Sadr-Ameli, Mohammad Ali   +2 more
core   +2 more sources

Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia [PDF]

, 2018
Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J., Patel, Jyoti Kandlikar, Patel, Parin J., Prystowsky, Eric N., Segar, Rachel   +4 more
core   +1 more source

Reprogramming the Myocardial Infarction Conductive Microenvironment with Superconductive Ionic Patch for Cardiac Function Repair

Advanced Science, EarlyView.
A super‐conductive ionic patch reprograms the post‐infarction microenvironment by enabling stable ionic migration and electrical signal transmission within damaged myocardium. The patch rapidly adheres to cardiac tissue, enhances conduction velocity, suppresses excitation‐contraction decoupling, and promotes structural and functional cardiac repair in ...
Changyong Wang, Zhuang Zhang, Qi Yin, Changgeng Xu, Linlin Liang, Siwei Li, Yuwei Zhao, Chunlan Wang, Jin Zhou   +8 more
wiley   +1 more source

The effect of revascularization on mortality and risk of ventricular arrhythmia in patients with ischemic cardiomyopathy

BMC Cardiovascular Disorders, 2020
Background There is clear evidence that patients with prior myocardial infarction and a reduced ejection fraction benefit from implantation of a cardioverter-defibrillator (ICD).
Ahmad Alkharaza, Mousa Al-Harbi, Ihab El-sokkari, Steve Doucette, Ciorsti MacIntyre, Christopher Gray, Amir Abdelwahab, John L. Sapp, Martin Gardner, Ratika Parkash   +9 more
doaj   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Modeling the Heart as a Communication System [PDF]

, 2014
Electrical communication between cardiomyocytes can be perturbed during arrhythmia, but these perturbations are not captured by conventional electrocardiographic metrics.
Aguilar-Rodríguez, José, Ashikaga, Hiroshi, Garland, Joshua, Gorsky, Shai, Lusczek, Elizabeth, Marquitti, Flávia Maria Darcie, Thompson, Brian, Wu, Degang   +7 more
core   +2 more sources

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Automatic Mode Switching in Atrial Fibrillation [PDF]

, 2005
Automatic mode switching (AMS) algorithms were designed to prevent tracking of atrial tachyarrhythmias (ATA) or other rapidly occurring signals sensed by atrial channels, thereby reducing the adverse hemodynamic and symptomatic consequences of a rapid ...
Antonio De, Simone, Enrico, Romano, Giuseppe, Stabile   +2 more
core  

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

Advanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani, Elena Mancinelli, Gabriele Tullii, Aleksandr Khudiakov, Cristiano Bortolotti, Shubham Tanwar, Peter J. Schwartz, Luca Sala, Maria Rosa Antognazza, Mario Caironi, Adrica Kyndiah   +10 more
wiley   +1 more source

Clinical and molecular characterization of a cardiac ryanodine receptor founder mutation causing catecholaminergic polymorphic ventricular tachycardia [PDF]

, 2015
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a difficult-to-diagnose cause of sudden cardiac death (SCD). We identified a family of 1400 individuals with multiple cases of CPVT, including 36 SCDs during youth.
Allegue, Catarina, Beltran-Alvarez, Pedro, Berne, Paola, Bosch Calero, Cristina, Brugada, Josep, Brugada, Ramon, Campuzano, Oscar, Iglesias, Anna, Pérez, Carmelo, Pérez, Guillermo J., Ruiz Hernandez, Pablo M., Scornik, Fabiana S., Wangüemert, Fernando   +12 more
core   +2 more sources