This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
Objective: to evaluate the structural and functional state of the right cardiac cavities in acute left ventricular myocardial infarction and in progressive chronic heart failure (CHF) in patients with coronary heart disease.Materials and methods.
L. I. Sergeyeva +2 more
doaj +1 more source
Left ventricular systolic function evaluated by strain echocardiography and relationship with mortality in patients with severe sepsis or septic shock. a systematic review and meta-analysis [PDF]
Sepsis-induced myocardial dysfunction is associated with poor outcomes, but traditional measurements of systolic function such as left ventricular ejection fraction (LVEF) do not directly correlate with prognosis.
Arcadipane, A +7 more
core +1 more source
Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim +8 more
wiley +1 more source
Right ventricular diastolic dysfunction in asthmatic patients
Asthmatic patients develop right heart affection from early stages through different mechanisms. The current study was performed aiming to assess the right ventricular diastolic dysfunction in different asthmatic stages.
K.E. Sobhy +3 more
doaj +1 more source
Acute Cyclophosphamide Hemorrhagic Myopericarditis: Dilemma Case Report, Literature Review and Proposed Diagnostic Criteria [PDF]
Cyclophosphamide is a potent DNA alkylating agent used in chemotherapy and immunosuppression. Although an old agent, its use in the present day has expanded for cases of refractory autoimmune disease.
Subeer Wadia
doaj +1 more source
Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis [PDF]
Objective: First-degree atrioventricular block is frequently encountered in clinical practice and is generally considered a benign process. However, there is emerging evidence that prolonged PR interval may be associated with adverse outcomes. This study
Barker, Diane +11 more
core +1 more source
NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu +15 more
wiley +1 more source
THE ROLE OF ECHOCARDIOGRAPHY IN ASSESSMENT OF HEART REMODELING IN PATIENTS WITH CTEPH
SUMMERY The study included 40 patients with CTEPH of different severity. All patients underwent 2D and 3D echocardiography to assess structure and function of right and left heart chambers, ventricular interaction, and ventricular-vascular coupling.
A. A. Belevskaya +3 more
doaj +1 more source
Peripartum cardiomyopathy: diagnosis and management [PDF]
No abstract ...
Coats, Caroline J. +5 more
core +1 more source

