Results 41 to 50 of about 228,142 (338)

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

Advanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren, Nurul Aisha Zainal Abidin, Allan Sun, Rui Gao, Yuxin Chen, Arian Nasser, Zihao Wang, Yunduo Charles Zhao, Alexander Dupuy, Anna Waterhouse, Qian Peter Su, Daniele Vigolo, Mike Chia Lun Wu, Lining Arnold Ju   +13 more
wiley   +1 more source

The efficacy and safety of intraoperative intravenous amiodarone in patients undergoing on-pump coronary artery bypass grafting surgery: a systemic review and PRISMA-compliant meta-analysis

Journal of Cardiothoracic Surgery
Background To evaluate the clinical efficacy and safety of intraoperative intravenous amiodarone for arrhythmia prevention in on-pump coronary artery bypass grafting (CABG) patients.
Jin-He Deng, Bin Jia, Yun-Tai Yao, The Evidence in Cardiovascular Anesthesia (EICA) Group   +3 more
doaj   +1 more source

Incidence and predictors of premature ventricular complexes following catheter ablation for atrial fibrillation [PDF]

, 2017
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia, and previous studies have focused on the epidemiology, mechanisms and risk factors for this global disease (Ryder and Benjamin 1999). Various studies have examined the mechanism,
Harvey, Joshua
core  

Altered excitation-contraction coupling in human chronic atrial fibrillation [PDF]

, 2012
This review focuses on the (mal)adaptive processes in atrial excitation-contraction coupling occurring in patients with chronic atrial fibrillation. Cellular remodeling includes shortening of the atrial action potential duration and effective refractory ...
Grandi, E., Pandit, S.V., Workman, A.J.
core   +1 more source

Spatially Programmable Electroadhesive Enables In Situ Site‐Selective Functional Coupling

Advanced Materials, EarlyView.
A light‐activated, in situ spatially programmable bioadhesive (STICH) enables microscale, site‐selective integration of bioelectronic devices with wet tissue. It achieves robust mechanical bonding and low‐impedance electrical coupling, enabling reconfigurable neuromodulation and directional electromechanical sensing in vivo and ex vivo.
Yuting Guo, Zhuoming Liang, Guoshi Xu, Zhen Gu, Yuheng Xu, Michael Raphael Panganiban, Xue Cai, Jet Yong Kiat Lim, Jiguang Zhang, Jingxiu Huang, Tingting Fan, Qi Gu, Yuxin Liu   +12 more
wiley   +1 more source

Intensive Exercise Training Improves Cardiac Electrical Stability in Myocardial‐Infarcted Rats

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundModerate exercise training has been shown to decrease sudden cardiac death post myocardial infarction. However, the effects of intensive exercise are still controversial.
Horesh Dor‐Haim, Chaim Lotan, Michal Horowitz, Moshe Swissa   +3 more
doaj   +1 more source

Mesencephalic Astrocyte‐Derived Neurotrophic Factor Binds BAX to Preserve Mitochondrial Homeostasis and Energy Metabolism for Relieving Myocardial Hypertrophy

Advanced Science, EarlyView.
MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang, Xinru Zhang, Baolong Wang, Haipeng Li, Dongshuo Xu, Yun Yang, Jialu Zhang, Wenbing Wang, Ren Zhang, Xinyu Wang, Yunfeng Cai, Shiyu Cao, Chao Hou, Changhui Wang   +13 more
wiley   +1 more source

Discordant Alternans as a Mechanism for Initiation of Ventricular Fibrillation In Vitro

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Ventricular tachyarrhythmias are often preceded by short sequences of premature ventricular complexes. In a previous study, a restitution‐based computational model predicted which sequences of stimulated premature complexes were most likely to
Laura M. Muñoz, Anna R. M. Gelzer, Flavio H. Fenton, Wei Qian, WeiYe Lin, Robert F. Gilmour, Niels F. Otani   +6 more
doaj   +1 more source

Electrical Storms in Brugada Syndrome: Review of Pharmacologic and Ablative Therapeutic Options [PDF]

, 2005
Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in
Haïssaguerre, M, Hocini, M, Maury, P
core   +2 more sources

Electrocardiographic patch devices and contemporary wireless cardiac monitoring. [PDF]

, 2015
Cardiac electrophysiologic derangements often coexist with disorders of the circulatory system. Capturing and diagnosing arrhythmias and conduction system disease may lead to a change in diagnosis, clinical management and patient outcomes.
Carlson, SK, Chang, PM, Doshi, RN, Fung, E, Grazette, LP, Huikuri, HV, Järvelin, MR, Peters, NS, Sangha, RS, Shinbane, JS   +9 more
core   +2 more sources