Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang+12 more
wiley +1 more source
113 healthy subjects with normal blood pressure and 26 patients with essential hypertension (BP 140-159/90-99 mm Hg) were inspected by echocardiography. All subjects were divided into 5 groups according to the blood pressure (BP) level.
A. V. Tuyev, Y. B. Hovayeva
doaj
Using Anatomical Markers for Left Ventricular Segmentation of Long Axis Ultrasound Images [PDF]
Left ventricular segmentation is essential for measuring left ventricular function indices. Segmentation of one or several images requires an initial guess of the contour. It is hypothesized here that creating an initial guess by first detecting anatomical markers, would lead to correct detection of the endocardium.
arxiv
Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature [PDF]
ObjectivePatients with severe left ventricular pressure overload secondary to aortic stenosis can present with signs and symptoms of heart failure despite normal left ventricular ejection fraction.
Dixon, Jennifer A.+9 more
core +1 more source
Protein‐Like Polymers Targeting Keap1/Nrf2 as Therapeutics for Myocardial Infarction
We describe a Keap1 targeting protein‐like polymer (PLP) which activates Nrf2, an important cytoprotective transcription factor for relieving myocardial infarction‐induced oxidative stress. This PLP increases cell survival in vitro in multiple relevant cardiac cell types and elicits pro‐reparative responses, improving cardiac function in a preclinical ...
Joshua M. Mesfin+17 more
wiley +1 more source
Real-time Assessment of Right and Left Ventricular Volumes and Function in Children Using High Spatiotemporal Resolution Spiral bSSFP with Compressed Sensing [PDF]
Background: Real-time (RT) assessment of ventricular volumes and function enables data acquisition during free-breathing. However, in children the requirement for high spatiotemporal resolution requires accelerated imaging techniques. In this study, we implemented a novel RT bSSFP spiral sequence reconstructed using Compressed Sensing (CS) and ...
arxiv
Left ventricular hypertrophy induced by weight excess in children and adolescents [PDF]
Background: Obesity is associated with left ventricular hypertrophy, an independent risk factor of cardiovascular morbidity. The aim of the present study was to evaluate obesity-induced left ventricular hypertrophy in overweight/obese children and ...
Galli-Tsinopoulou, Assimina+4 more
core +1 more source
Arterial switch for pulmonary venous obstruction complicating mustard procedure [PDF]
Two patients underwent an arterial switch procedure for the relief of severe pulmonary venous obstruction complicating a Mustard procedure. Without preparatory pulmonary banding, both patients had adequate left ventricular function due to secondary ...
Bogers, A.J.J.C. (Ad)+3 more
core +1 more source
Biomechanical‐to‐electrical energy conversion devices are uniquely suited for self‐driven physiological information monitoring and powering human–computer interaction systems. These devices based on micro‐/nanoarchitectured inorganic dielectric materials (MNIDMs) have shown ultrahigh electromechanical performance and thus great potential for practical ...
Jia‐Han Zhang+12 more
wiley +1 more source
Background Until recently acute inflammatory peri-myocardial syndromes have been associated with global rather regional left ventricular (LV) dysfunction. Recent advances in cardiac imaging with echocardiographic techniques and magnetic resonance imaging
Leitman Marina+4 more
doaj +1 more source