Results 251 to 260 of about 1,014,709 (316)

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Effects of weight loss after sleeve gastrectomy on left ventricular myocardial work in obese patients. [PDF]

Front Cardiovasc Med
Ding X, Zhang X, Zhao J, Wei C, Luo S, Yuan J, Zhu H.   +6 more
europepmc   +1 more source

Sex Differences in Diastolic Function Following Myocardial Infarction on Doppler Echocardiography. [PDF]

Echocardiography
Chan NI, Atherton JJ, Thomas L, Whalley G, Stewart P, Mallouhi M, Vollbon W, Prasad SB.   +7 more
europepmc   +1 more source

Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB

Animal Models and Experimental Medicine, EarlyView.
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang, Jie‐Jian Kou, Hong‐Da Zhang, Xin‐Mei Xie, Yun‐Feng Zhou, Ping Yuan, Xiao‐Bin Pang, Lu‐Ling Zhao, Jing Qiu, Yang‐Yang He   +9 more
wiley   +1 more source

Exercise enhances cardiomyocyte mitochondrial homeostasis to alleviate left ventricular dysfunction in pressure overload induced remodelling. [PDF]

Sci Rep
Ma Z, Cen Y, Xun W, Mou C, Yu J, Hu Y, Liu C, Sun J, Bi R, Qiu Y, Ding M, Jin L.   +11 more
europepmc   +1 more source

In vivo toxic and lethal cardiorespiratory effects of a synthetic quaternary ammonium salt derivative of haloperidol in mice

Animal Models and Experimental Medicine, EarlyView.
Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao, Binger Lu, Jinhua Yang, Xiaowan Wang, Shuxian Li, Hongbo Fu, Fenfei Gao   +6 more
wiley   +1 more source

Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology. [PDF]

Ren Fail
Jin M, Ma L, Li B, Huang X, Chen M.
europepmc   +1 more source

Refining the adriamycin‐induced focal segmental glomerulosclerosis mouse model to improve reproducibility and animal welfare

Animal Models and Experimental Medicine, EarlyView.
This study suggested the instability of Adriamycin (ADR) in aqueous solution as the main contributor to large ADR dose variations in literature of the ADR‐induced mouse model of focal segmental glomerulosclerosis (FSGS). We confirmed that freshly prepared ADR solution dosed at 10.5 mg/kg to be optimal in reliably producing FSGS pathology in BALB/c mice
Haochen Jiang, Salma Althobaiti, Braeden Pinkerton, Xin Fu, Zhenshan Jia, Kirk W. Foster, Geoffrey M. Thiele, Troy J. Plumb, Dong Wang   +8 more
wiley   +1 more source

Regional Cerebral Atrophy Contributes to Personalized Survival Prediction in Amyotrophic Lateral Sclerosis: A Multicentre, Machine Learning, Deformation‐Based Morphometry Study

Annals of Neurology, EarlyView.
Objective Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve individual survival predictions.
Isabelle Lajoie, Canadian ALS Neuroimaging Consortium (CALSNIC), Sanjay Kalra, Mahsa Dadar   +3 more
wiley   +1 more source

Optimizing MitraClip Outcomes: The Case for Routine Iatrogenic ASD Closure. [PDF]

Clin Med Insights Cardiol
Streb W, Fiszer R, Mitręga K, Podolecki T, Kurek T, Lazar M, Kowalska W, Wizner A, Stanjek-Cichoracka A, Kalarus Z.   +9 more
europepmc   +1 more source