Results 51 to 60 of about 529,220 (309)

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

Evaluation of Left Ventricular Trabeculae in Patients with Hypertension Using Cardiac Magnetic Resonance Imaging

CT Lilun yu yingyong yanjiu
Objective: To explore the feasibility of cardiac magnetic resonance imaging (MRI) for evaluating the complexity of the left ventricular trabeculae in patients with hypertension, analyze the relationship between MRI characteristics and left ventricular ...
Yue WANG, Hongwei CAO, Jiancheng SHI, Huijie REN, Bailin WU, Budong CHEN   +5 more
doaj   +1 more source

Gender differences in cardiac left ventricular mass and function: clinical and experimental observations [PDF]

, 2014
Background: The aim of this study was to evaluate gender-associated impact on left ventricular mass (LVM) and on left ventricular function (LVF) in humans and rats with aging. Methods: Myocyte area and collagen volume fraction (CVF) were studied in rats.
Aiello, Ernesto Alejandro, Diaz, Alejandro, Ennis, Irene Lucia, Escudero, Eduardo Manuel, Orlowski, Alejandro, Pinilla, Oscar Andres   +5 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Acute left ventricular dysfunction secondary to right ventricular septal pacing in a woman with initial preserved contractility: a case report

Journal of Medical Case Reports, 2011
Introduction Right ventricular apical pacing-related heart failure is reported in some patients after long-term pacing. The exact mechanism is not yet clear but may be related to left ventricular dyssynchrony induced by right ventricular apical pacing ...
Gribaa Rim, Neffeti Elyes, Lagren Afef, Kacem Slim, Azzez Soufiene, Ouali Sana, Remedi Fahmi, Boughzela Essia   +7 more
doaj   +1 more source

Relationship between left ventricular mechanical synchrony and left ventricular systolic function: a CZT-SPECT analysis

BMC Cardiovascular Disorders, 2022
Background CZT-SPECT has good agreement in the evaluation of mechanical synchronization compared with conventional SPECT. The aim of this study was to evaluate the correlation between left ventricular mechanical contraction synchrony and left ventricular
Qiting Sun, Ruiliang Huang, Songhai Fu, Chen Wu, Xuliang Guo, Tianliang Li, Yuehong Hou, Fei Wang, Rui Xi, Sijin Li   +9 more
doaj   +1 more source

Effect of Growth Hormone (hGH) Replacement Therapy on Physical Work Capacity and Cardiac and Pulmonary Function in Patients with hGH Deficiency Acquired in Adulthood. [PDF]

, 1995
The effects of 6 months of replacement therapy with recombinant human GH (hGH) on physical work capacity and cardiac structure and function were investigated in 20 patients with hGH deficiency of adult onset in a double blind, placebo-controlled trial ...
Huber, Rudolf M., Klauss, Volker, Müller, Otto A., Nass, Ralf, Schopohl, Jochen, Strasburger, Christian J.   +5 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Thyroid hormone levels within reference range are associated with heart rate, cardiac structure, and function in middle-aged men and women [PDF]

, 2013
Background: Triiodothyronine (T3) has many effects on the heart, and marked changes in cardiac function and structure occur in patients with (subclinical) thyroid disease. We investigated whether between-subject variation in thyroid hormone levels within
De Buyzere, Marc, Gillebert, Thierry, Kaufman, Jean, Rietzschel, Ernst, ROEF, GREET, Taes, Youri, Van daele, Caroline   +6 more
core   +1 more source