Abstract Cells derived from the endocardium, epicardium, cardiac neural crest, and second heart field play a critical role in the formation of the valvuloseptal structures of the heart. Previous studies have shown that the expression of the transcription factor SOX9 in these cell populations is essential in the regulation of this process.
Hannah G. Tarolli +6 more
wiley +1 more source
Permanent Cardiac Pacing in Children: A 30-Year Follow-Up Retrospective Study in a Single Pediatric Asian Center. [PDF]
Chan JC +12 more
europepmc +1 more source
Abstract The heart is the central organ of the cardiovascular system. The myocardium is composed of a three‐dimensional network of fibers arranged in clockwise and counterclockwise helices, which are essential for proper cardiac contraction. This study aimed to describe the stratigraphic and morpho‐functional pattern of the porcine myocardium to ...
Mauricio Oliveira da Silva +3 more
wiley +1 more source
The Effect of Transpulmonary Pressure-Guided Positive End-Expiratory Pressure Titration on Pulmonary Arterial Compliance in Acute Respiratory Distress Syndrome Patients: A Single-Center, Randomized Controlled Pilot Pathophysiological Study. [PDF]
Tang X +12 more
europepmc +1 more source
Disulfide Bond–Modified Proteomics Reveals the Effects of Riboflavin on Protein Folding Dynamics
Riboflavin deficiency impairs oxidative protein folding, causing ER misfolded protein accumulation, CHOP activation, and apoptosis, revealing a role of riboflavin in proteostasis. ABSTRACT Riboflavin is a crucial micronutrient essential for maintaining cellular homeostasis, acting as an important precursor for flavoproteins that utilize flavin ...
Bo Zhang, Shuisheng Hou, Jing Tang
wiley +1 more source
Catheter ablation for idiopathic premature ventricular complexes: a single-centre experience. [PDF]
Sia RI +9 more
europepmc +1 more source
Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo +7 more
wiley +1 more source
Newly Detected Atrial Flutter After Enclomiphene Dose Escalation in a Patient With Prior Mitral Valve Repair and Chronic Immune Thrombocytopenia: A Case Report. [PDF]
Tariq MN, Abdel Halim AT, Evans JA.
europepmc +1 more source
Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald +9 more
wiley +1 more source
Right Ventricular Function and Pulmonary Arterial Coupling in Paediatric Obstructive Sleep Apnea. [PDF]
Chan YY +11 more
europepmc +1 more source

