Results 201 to 210 of about 7,749,428 (298)

A rhesus macaque model of α‐dystroglycanopathy caused by a POMT1 splice altering variant

Animal Models and Experimental Medicine, EarlyView.
Rhesus macaques homozygous for a naturally occurring spice altering variant in the POMT1 gene develop lissencephaly, microphthalmia, and muscular contracture. The presentation models severe presentation of the human Walker‐Warburg syndrome. Abstract Background Biallelic mutations in genes associated with α‐dystroglycan glycosylation manifest in a ...
Anya Nordlund, Brian LaMendola, Nathan P. Crilly, Seth Kittle, Betsy M. Ferguson, Anne D. Lewis, Jeff Wall, Samuel M. Peterson   +7 more
wiley   +1 more source

Right Ventricular Isovolumetric Relaxation Time is Associated with Pulmonary Vascular Load and Functional Limitation in Chronic Obstructive Pulmonary Disease. [PDF]

Int J Chron Obstruct Pulmon Dis
Dong F, Tanaka Y, Okamura K, Higa K, Kaburaki S, Sato Y, Tanaka T, Shimizu A, Takeuchi S, Kubota Y, Taniuchi N, Kamio K, Kasahara K, Wu L, Seike M, Hino M, Kimura H.   +16 more
europepmc   +1 more source

Noninvasive Evaluation of Right Ventricular Function [PDF]

Journal of the Royal Society of Medicine, 1983
openaire   +2 more sources

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

Animal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa, Masaki Watanabe, Koyuki Kawamoto, Momoka Hiratsuka, Takeru Sasaki, Nobuya Sasaki   +5 more
wiley   +1 more source

A structured 5-question approach for echocardiographic evaluation of undifferentiated shock. [PDF]

Echo Res Pract
Colebourn C, Fisher R.
europepmc   +1 more source

Adenosine monophosphate–activated protein kinase activation is associated with suppression of NLRP3 inflammasome–mediated neuroinflammation in a weight‐drop model of traumatic brain injury in Sprague–Dawley rats

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the study's schematic model. Adenosine monophosphate–activated protein kinase (AMPK) activators exhibited neuroprotection in the weight‐drop model of traumatic brain injury by improving cognition and regulating oxidative stress, microglial activation, and nucleotide‐binding oligomerization domain, leucine‐rich repeat,
Triveni Kodi, Paka Sravan Kumar, Krishnadas Nandakumar, Anoop Kishore   +3 more
wiley   +1 more source

Echocardiographic Phenomapping in HFpEF: From Imaging Biomarkers to Precision Cardiovascular Medicine. [PDF]

Echocardiography
Shahverdi E, Schulz M, Schneider C, Lange M.   +3 more
europepmc   +1 more source

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community

Annals of Neurology, EarlyView.
Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta, Davide Liborio Vetrano, Erika J. Laukka, Grégoria Kalpouzos, Javier Oltra, Debora Rizzuto, Marco Canevelli, Claudia Fredolini, Chengxuan Qiu, Bengt Winblad, Laura Fratiglioni, Giulia Grande   +11 more
wiley   +1 more source

Right ventricular-pulmonary arterial uncoupling and venous excess in normotensive pulmonary embolism shock. [PDF]

Crit Care
Gasca-Aldama JC, López-Rodríguez KH, Carrasco-Flores MA, Morales-Ferrer JÁ, Marché-Fernández OA, Vidals-Sánchez M, Juárez-León JE, Moya-Alfaro ML, González-Escudero EA.   +8 more
europepmc   +1 more source