Results 31 to 40 of about 7,749,428 (298)

Right Heart Size and Right Ventricular Reserve in Pulmonary Hypertension: Impact on Management and Prognosis

Diagnostics, 2020
Various parameters reflecting right heart size, right ventricular function and capacitance have been shown to be prognostically important in patients with pulmonary hypertension (PH).
Ekkehard Grünig, Christina A. Eichstaedt, Rebekka Seeger, Nicola Benjamin   +3 more
doaj   +1 more source

Right ventricular dyssynchrony in patients with pulmonary hypertension is associated with disease severity and functional class

Cardiovascular Ultrasound, 2005
Background Abnormalities in right ventricular function are known to occur in patients with pulmonary arterial hypertension. Objective Test the hypothesis that chronic elevation in pulmonary artery systolic pressure delays mechanical activation of the ...
Murali Srinivas, Suffoletto Matthew, Rajagopalan Navin, Dohi Kaoru, López-Candales Angel, Gorcsan John, Edelman Kathy   +6 more
doaj   +1 more source

Subtle right ventricular dysfunction in asymptomatic chronic heavy cigarette smokers: a speckle tracking case-control study

The Egyptian Heart Journal, 2021
Background Chronic heavy cigarette smoking can affect the right ventriclular function. The standard echocardiography may not show early right ventricular functional changes, and a more sensitive measure is needed. The aim of this work was to evaluate the
Mohammad Iqbal Janhangeer, Ghada Youssef, Weal El Naggar, Dalia El Remisy   +3 more
doaj   +1 more source

Evaluation of the right ventricular function in dogs with brachycephalic syndrome before and after rhinoplasty

Brazilian Journal of Veterinary Medicine, 2022
Brachycephalic dogs are usually affected by primary and secondary anatomical changes in the airways that contribute to the brachycephalic syndrome. Chronically, these changes contribute to an increase in pulmonary arterial pressure and right cardiac ...
Daniel Carvalho Hainfellner, Daniel de Almeida Balthazar, Cristiano Chaves Pessoa da Veiga, Aguinaldo Francisco Mendes Junior, Ana Maria de Barros Soares, Juliana Silva do Carmo, Karen Denise da Silva Macambira Barbosa, Nathalia Marques de Oliveira Lemos, Carolina do Valle Aben Athar, Alexandre José Rodrigues Bendas, Bruno Alberigi, Mário dos Santos Filho, Jonimar Pereira Paiva   +12 more
doaj   +1 more source

Partitioning the Right Ventricle Into 15 Segments and Decomposing Its Motion Using 3D Echocardiography-Based Models: The Updated ReVISION Method

Frontiers in Cardiovascular Medicine, 2021
Three main mechanisms contribute to global right ventricular (RV) function: longitudinal shortening, radial displacement of the RV free wall (bellows effect), and anteroposterior shortening (as a consequence of left ventricular contraction).
Márton Tokodi, Levente Staub, Ádám Budai, Bálint Károly Lakatos, Máté Csákvári, Ferenc Imre Suhai, Liliána Szabó, Alexandra Fábián, Hajnalka Vágó, Zoltán Tősér, Béla Merkely, Attila Kovács   +11 more
doaj   +1 more source

Right ventricular function in systemic hypertension [PDF]

Journal of Human Hypertension, 1998
The aim of the study was the assessment of right ventricular (RV) structure and diastolic function in hypertensive subjects. The study group consisted of 44 patients with untreated, mild to moderate essential systemic hypertension. All the patients were in sinus rhythm, no symptoms of congestive heart failure, ischaemic or valvular heart disease and ...
W, Myśliński, J, Mosiewicz, E, Ryczak, W, Barud, A, Biłan, R, Palusiński, J, Hanzlik   +6 more
openaire   +2 more sources

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Improvement of left ventricular systolic function after intervention on right ventricular hemodynamics

Annals of Pediatric Cardiology
Background: The importance of right–left ventricular interactions is increasingly recognized in patients with congenital heart disease. Interventions to improve right ventricular volume/pressure overloading may result in improvement of left ventricular ...
James Wiley, Whitney Fairchild, Anudeep K. Dodeja, Cesar I. Mesia, Caitlin M. Heyden, Shailendra Upadhyay   +5 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Molecular genetics of arrhythmogenic right ventricular cardiomyopathy in South Africa [PDF]

, 2011
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable disorder characterised by progressive degeneration of the right ventricular myocardium, arrhythmias and an increased risk of sudden death at a young age. Fourteen chromosomal loci have
Blanckenberg, Janine
core   +1 more source