Results 51 to 60 of about 11,454,093 (341)

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension [PDF]

, 2015
The effects of increased intra-abdominal pressure (IAP) on cardiovascular function are well recognized and include a combined negative effect on preload, afterload and contractility.
De Keulenaer, Bart L, De Waele, Jan, Malbrain, Manu LNG   +2 more
core   +1 more source

Long‐Term Temporal Profile of Motor Recovery After Intracerebral Hemorrhage

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Limited data is available to describe the temporal profile of long‐term recovery over 1 year after the stroke in patients with spontaneous intracerebral hemorrhage (ICH). Methods A registered multicentral cohort was conducted to consecutively include non‐herniated supratentorial ICH patients from November 2013 to January 2023 ...
Yan Zheng, Fu‐Xin Lin, Ling‐Yun Zhuo, Jian‐Cai Chen, Xin Ge, Xiang‐Lin Chen, Xue‐Jiao Wang, Zhi‐Gang Yao, You‐Liang Tong, Bo Xie, Bai‐Hai Guo, Zhao‐Sheng Sun, Zhi‐Hua Tian, Ping Qiu, Xin‐Ru Lin, Qiu He, Shu‐Na Huang, Ke Ma, Fang‐Yu Wang, Huang‐Cheng Shang‐Guan, Wen‐Hua Fang, Deng‐Liang Wang, Ying Fu, Yuan‐Xiang Lin, De‐Zhi Kang   +24 more
wiley   +1 more source

Physiological basis in the assessment of myocardial mechanics using speckle-tracking echocardiography 2D. Part I [PDF]

Journal of Ultrasonography, 2016
In this paper, the authors attempt to concisely present the anatomical and pathophysiological bases as well as the principles for echocardiographic evaluation of mechanical aspects of cardiac function based on speckle tracking method. This technique uses
Wojciech Mądry, Maciej Aleksander Karolczak   +1 more
doaj   +1 more source

Effects of anesthesia on conventional and speckle tracking echocardiographic parameters in a mouse model of pressure overload [PDF]

, 2015
Genetically‑modified mice are widely applied in cardiovascular studies as model organisms. Echocardiography is a key tool for evaluating cardiac and hemodynamic functions in mice.
Cao, Ming, He, Wei, Manyande, Anne, Wang, Guan, Wang, Jinli, Wu, Xiaofen, Zhang, Cuntai, Zhang, Le   +7 more
core   +1 more source

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald, Michela Guglieri, Dragana Vučinić, Gyula Acsadi, John F. Brandsema, Claudio Bruno, Erika L. Finanger, Amy Harper, Mercedes Lopez Lobato, Riccardo Masson, Nuria Muelas, Francina Munell, Yoram Nevo, Yann Péréon, Han Phan, Valeria A. Sansone, Mariacristina Scoto, Tracey Willis, Richard S. Finkel, Krista Vandenborne, Sara Cazzaniga, Silvia Montrasio, Federica Alessi, Paolo Bettica, Eugenio Mercuri, for the Givinostat Study 51 Investigators, the Cooperative International Neuromuscular Research Group (CINRG) Duchenne Natural History Study (DNHS) Investigators, the ImagingDMD Investigators, Enrico Bertini, Giacomo Pietro Comi, Eugenio Maria Mercuri, Giuseppe Vita, Sonia Messina, Claudio Bruno, Riccardo Masson, Valeria Sansone, Nathalie Goemans, Liesbeth De Waele, Laurent Servais, Teresa Gidaro, Odile Boespflug‐Tanguy, Yann Péréon, Jessika Johannsen, Astrid Blaschek, Ulrike Schara‐Schmidt, Erik Niks, Imelda de Groot, Saskia Houwen‐van Opstal, Andres Nascimento, Juan Jesus Vilchez, Nuria Muelas, Francina Munell, Marcos Madruga Garrido, Mercedes Lopez Lobato, Michaela Guglieri, Tracey Willis, Stefan Spinty, Daniel Hawcutt, Mariacristina Scoto, Jean K. Mah, Laura McAdam, Kathryn Selby, Katherine Mathews, Craig McDonald, Craig Zaidman, Barry Byrne, John Brandsema, Gyula Acsadi, Chamindra Laverty, Amy Harper, Erika Finanger, Han Phan, Yoram Nevo, Vedrana Milic Rasic, Dragana Vucinic   +74 more
wiley   +1 more source

Tako-tsubo cardiomyopathy observed in a patient with sepsis and transient hyperthyroidism

Monaldi Archives for Chest Disease, 2016
ischemic stroke with residual left hemiparesis, was admitted to our hospital because of dyspnoea with clinical evidence of acute pulmonary edema.
Filippo M. Sarullo, Luigi Americo, Salvatore Accardo, Sergio Cicero, Rossella Schicchi, Maria Schirò, Antonio Castello   +6 more
doaj   +1 more source

Straining With the Ventricular Assist Device and Right Ventricular Function

Journal of the American College of Cardiology, 2013
We read with great interest the paper by Grant et al. ([1][1]) in which they provide an analysis to support the use of strain imaging as a unique echocardiographic measure to predict right ventricular (RV) failure in patients undergoing left ventricular assist device (LVAD) placement.
Ulrich P. Jorde, Nir Uriel, Sunu S. Thomas   +2 more
openaire   +3 more sources

Early diagnosis of cardiovascular diseases in workers: role of standard and advanced echocardiography [PDF]

, 2018
Cardiovascular disease (CVD) still remains the main cause of morbidity and mortality and consequently early diagnosis is of paramount importance. Working conditions can be regarded as an additional risk factor for CVD. Since different aspects of the job
Capotosto, Lidia, DE SIO, Simone, Massoni, Francesco, Ricci, Serafino, Vitarelli, Antonio   +4 more
core   +3 more sources

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source