Results 71 to 80 of about 31,412 (299)

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll, Yves Alembik, Marie‐Paule Roth   +2 more
wiley   +1 more source

Left ventricular mid-cavity obstruction: A novel cause of duct-dependent systemic circulation in a newborn

Annals of Pediatric Cardiology
Accessory mitral valve tissue is a rare congenital anomaly that may cause left ventricular outflow tract obstruction. This may be the first case report in a neonate, describing accessory mitral valve tissue producing a significant left ventricular ...
Salim Nasser Al-Maskari, Madan Mohan Maddali, Ghida Mubarak Al-Muzaini, Halima Adam Al-Hashmi   +3 more
doaj   +1 more source

Anaesthetic management of a patient with hypertrophic obstructive cardiomyopathy posted for emergency lower segment caesarean section

Journal of Obstetric Anaesthesia and Critical Care, 2017
Hypertrophic cardiomyopathy is characterised by asymmetric hypertrophy of the interventricular septum causing intermittent obstruction of the left ventricular outflow tract.
Pradnya M Bhalerao, Pritam B Adsule, Radhika M Marathe   +2 more
doaj   +1 more source

Myocardial energy depletion and dynamic systolic dysfunction in hypertrophic cardiomyopathy [PDF]

, 2016
Evidence indicates that anatomical and physiological phenotypes of hypertrophic cardiomyopathy (HCM) stem from genetically mediated, inefficient cardiomyocyte energy utilization, and subsequent cellular energy depletion.
A Shah, AA Geisterfer-Lowrance, AC Hoskins, BC Knollman, BJ Maron, BJ Maron, C Ferrantini, C O'Mahony, C O'Mahony, CJ Neil, CS Redwood, CW Tong, CY Ho, DG Hardie, DK Dawson, DT Lucas, DV Unverferth, E Blair, EM Green, ER Witjas-Paalberends, ER Witjas-Paalberends, F Baudenbacher, F Cecchi, F Lan, F Merante, F Pelliccia, H Ashrafian, H Ashrafian, H Ashrafian, H Watkins, HM Conklin, HP Beyerbacht, I Barac, I Olivotto, I Olivotto, J Ross, J Ross Jr, J Ross Jr, J Ross Jr., J Tardiff, JA Wagner, JE Brush Jr, JG Crilley, JO Ormerod, JR Po, Julian O. M. Ormerod, K Abozguia, K Abozguia, K Gehmlich, K Okeie, K Sakata, K Unno, L Thierfelder, M Bunse, M Mahmod, M Mahmod, M Sherrid, M Spindler, Mark V. Sherrid, Michael P. Frenneaux, ML Alves, MM Javadpour, MS Maron, MV Sherrid, MV Sherrid, MV Sherrid, MV Sherrid, N Günal, OA Breithardt, PT O'Gara, R Coppini, R Lodi, R Lodi, RC Saumarez, RH Chan, RO3rd Cannon, RO3rd Cannon, S Dass, S Huke, S Huke, S Ishiwata, S Marston, S Neubauer, S Neubauer, S Sasayama, S Singh, SA Timmer, SA Timmer, SA Timmer, SB Danik, SG Sirenko, SJ van Dijk, SS Lele, TB Levine, V Sequeira, WI Jung, Y Matsumura, Y Mishiro, YM Cha   +98 more
core   +1 more source

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

Animal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong, Wei Qian, Deji Song, Kang Li, Li Zhang, Li Shi   +5 more
wiley   +1 more source

Subpulmonary membrane: A rare cause of right ventricular outflow tract obstruction

Annals of Pediatric Cardiology, 2023
Subpulmonary membrane is a rare cause of right ventricular outflow tract (RVOT) obstruction, and only a few case reports exist with or without associated ventricular septal defect. We report a series of three cases with subpulmonary membrane causing RVOT
Rajat Gupta, Garima Garg, Tek Singh Mahant   +2 more
doaj   +1 more source

Changes in left atrial deformation in hypertrophic cardiomyopathy: Evaluation by vector velocity imaging. [PDF]

, 2012
OBJECTIVES: Hypertrophic cardiomyopathy (HCM) represents a generalized myopathic process affecting both ventricular and atrial myocardium. We assessed the global and regional left atrial (LA) function and its relation to left ventricular (LV) mechanics ...
Badran, HM, Faheem, N, Hassan, H, Nazmy, A, Saadan, H, Soltan, G, Yacoub, MH   +6 more
core   +2 more sources

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

Animal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen, Xijia Shao, Xiulin Zhang, Ningning Zhang, Xiao Chen, Guangxin Yue, Jiangping Song   +6 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source