Results 161 to 170 of about 101,269 (365)

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience [PDF]

open access: diamondExperimental Physiology, EarlyView.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David Hutchings   +3 more
openalex   +2 more sources

The Sooner, the Better: Neuroprotective Strategies in Fetuses With Congenital Heart Disease

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion and oxygenation, which negatively affects brain growth and maturation.
Maaike Nijman   +7 more
wiley   +1 more source

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

An Acute Ischemic Stroke After the Retrograde Transaortic Manipulation

open access: yesClinical Case Reports
Acute ischemic stroke (AIS) during radiofrequency ablation of premature ventricular complexes (PVC) patients was rarely reported. This is the first case report on AIS during catheter ablation of PVC that highlighted that AIS could be encountered in some ...
Juan Xu   +6 more
doaj   +1 more source

Co‐occurrence of late potential and discrete prepotential on ablation site in a case of cardiac crux located premature ventricular complexes successfully ablated within the middle cardiac vein

open access: yesJournal of Arrhythmia, 2019
Some premature ventricular complexes (PVCs) originate from the coronary venous system. The great cardiac vein and the anterior cardiac vein are the most frequent localizations.
Kamil Gulsen   +6 more
doaj   +1 more source

CRPPA exon 6–9 deletion as a founder mutation in Chinese patients with dystroglycanopathy

open access: yesPediatric Investigation, EarlyView.
Analysis of sixteen Chinese dystroglycanopathy patients reveals a founder mutation (CRPPA exon 6–9 deletion) in 25% of cases and expands the phenotypic spectrum from severe muscle‐eye‐brain disease to limb‐girdle muscular dystrophy. ABSTRACT Importance Dystroglycanopathies (DGPs) are a group of muscular dystrophies with abnormal glycosylation of ...
Jihang Luo   +18 more
wiley   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

open access: yesRheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

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