Results 91 to 100 of about 188,365 (337)

Impact of sinus rhythm versus atrial fibrillation on left ventricular remodeling after transcatheter aortic valve replacement [PDF]

open access: hybrid, 2021
Jakob Ledwoch   +9 more
openalex   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

CLINICAL PREDICTIVE VALUE OF TISSUE INHIBITOR OF METALLOPROTEINASE-1 IMYOCARDIAL REMODELING DEVELOPMENT IN PATIENTS HAVING Q-WAVE MYOCARDIAL INFARCTION

open access: yesАтеросклероз, 2019
In this paper we thought to investigate clinical value of tissue inhibitor of metalloproteinase-1 (TIMP-1) in predicting left ventricular (LV) myocardial remodeling in patients having Q-wave myocardial infarction (Q-wave MI).
A. S. Vorobyev   +5 more
doaj   +1 more source

Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy. [PDF]

open access: yes, 2017
BackgroundHistone deacetylase (HDAC) inhibitors are promising therapeutics for various forms of cardiac diseases. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle (SV) heart disease ...
A Cevik   +49 more
core   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

open access: yesAdvanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu   +17 more
wiley   +1 more source

The effect of rosuvastatin on inflammation, matrix turnover and left ventricular remodeling in dilated cardiomyopathy: a randomized, controlled trial.

open access: yesPLoS ONE, 2014
BackgroundDilated cardiomyopathy is characterized by left ventricular dilatation and dysfunction. Inflammation and adverse remodeling of the extracellular matrix may be involved in the pathogenesis.
Kaspar Broch   +12 more
doaj   +1 more source

Racial differences of right ventricular remodelling in systemic hypertension unveiled by multiparametric cardiovascular magnetic resonance [PDF]

open access: bronze, 2022
Aqeel T Mohamed   +11 more
openalex   +1 more source

Left ventricular assist device-induced reverse ventricular remodeling

open access: yesProgress in Cardiovascular Diseases, 2000
Left ventricular assist devices provide chronic pressure and volume unloading of the dilated left ventricle in patients with end-stage heart failure. This is associated with reverse structural remodeling (normalization of the passive pressure-volume relationship), reverse molecular remodeling (increased expression of several genes involved in calcium ...
D, Burkhoff   +4 more
openaire   +2 more sources

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue   +13 more
wiley   +1 more source

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