Results 91 to 100 of about 123,523 (307)

The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]

, 2009
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
Allan Struthers, Jacob George, George, Jacob, Struthers, Allan   +3 more
core   +1 more source

Right ventricular remodeling [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2006
Anderson, Robert H., Lunkenheimer, Paul P.   +1 more
openaire   +2 more sources

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

The impact of dose of the angiotensin-receptor blocker valsartan on the post-myocardial infarction ventricular remodeling: study protocol for a randomized controlled trial

Trials, 2011
Background Angiotensin-converting enzyme inhibitors and the angiotensin-receptor blocker valsartan ameliorate ventricular remodeling after myocardial infarction (MI).
Cho Young-Rak, Kim Young-Dae, Park Tae-Ho, Park Kyungil, Park Jong-Sung, Baek Heekyung, Choi Sun-Young, Kim Kee-Sik, Hong Taek-Jong, Yang Tae-Hyun, Hwang Jin-Yong, Park Jong-Seon, Hur Seung-Ho, Lee Sang-Gon   +13 more
doaj   +1 more source

Biomarkers of ventricular remodelling in African hypertensives.

, 2013
Includes abstract.Includes bibliographical references.There is substantial evidence that the burden of hypertension, hypertension with left ventricular hypertrophy and hypertensive heart failure is very enormous in sub-Saharan Africa.
Dike, Ojji
core  

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Ventricular remodeling in heart failure.

, 2013
(A) Ventricular remodeling of major ion channel subunits and accessory proteins in heart failure. (B) Regional specificity of targets in failing and nonfailing hearts of both genders.
Christina M. Ambrosi (276349), Jeanne M. Nerbonne (276351), Igor R. Efimov (276352), Kathryn A. Yamada (276350)   +3 more
core   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Gender differences of atrial and ventricular remodeling and autonomic tone in nonelite athletes

, 2011
Veteran endurance athletes have an increased risk of developing atrial fibrillation (AF), with a striking male predominance. We hypothesized that male athletes were more prone to atrial and ventricular remodeling and investigated the signal-averaged P ...
Matthias Wilhelm, Ilca Wilhelm, Schmid, Jean-Paul, Wilhelm, Matthias, Roten, Laurent, Hugo Saner, Hildegard Tanner, Jean-Paul Schmid, Tanner, Hildegard, Wilhelm, Ilca, Saner, Hugo, Laurent Roten   +11 more
core   +1 more source

The multi-modality cardiac imaging approach to the Athlete's heart: an expert consensus of the European Association of Cardiovascular Imaging [PDF]

, 2015
peer reviewedThe term 'athlete's heart' refers to a clinical picture characterized by a slow heart rate and enlargement of the heart. A multi-modality imaging approach to the athlete's heart aims to differentiate physiological changes due to intensive ...
Galderisi, Maurizio, Popescu, Bogdan A., Cosyns, B, Petersen, SE, Cardim, Nuno, DAVIN, Laurent, Schroeder, S, Kitsiou, Anastasia, Cosyns, Bernard, Lancellotti, Patrizio, Petersen, Steffen E., Habib, G, Kitsiou, A, Edvardsen, T, Davin, L, Cardim, N, Bruder, Oliver, Popescu, Bogdan Alexandru, Burgstahler, C, D'Andrea, Antonello, Donal, E, Bruder, O, Plein, S, Freitas, A, Freitas, Antonio, Burgstahler, Christof, Galderisi, M, Edvardsen, Thor, Donal, Erwan, Lancellotti, P, Plein, Sven, D'Andrea, A, Schroeder, Stephen, Habib, Gilbert, Popescu, BA   +34 more
core   +1 more source