Results 21 to 30 of about 1,071,989 (385)
HDAC-dependent ventricular remodeling [PDF]
Trends in Cardiovascular Medicine, 2013 Heart failure, a syndrome culminating the pathogenesis of many forms of heart disease, is highly prevalent and projected to be increasingly so for years to come. Major efforts are directed at identifying the means of preventing, slowing, or possibly reversing the unremitting progression of pathological stress leading to myocardial injury and ultimately
Min, Xie, Joseph A, Hill
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Diabetes Care, 2020 OBJECTIVE To determine the effects of dapagliflozin in patients with heart failure (HF) and type 2 diabetes mellitus (T2DM) on left ventricular (LV) remodeling using cardiac MRI. RESEARCH DESIGN AND METHODS We randomized 56 patients with T2DM and HF with
Jagdeep S. Singh +13 more
semanticscholar +1 more source
Thioredoxin and ventricular remodeling [PDF]
Journal of Molecular and Cellular Cardiology, 2006 Increasing bodies of evidence indicate that reactive oxygen species (ROS) produced by mitochondria and other sources play an essential role in mediating ventricular remodeling after myocardial infarction and the development of heart failure. Antioxidants scavenge ROS, thereby maintaining the reduced environment of cells and inhibiting ventricular ...
Tetsuro, Ago, Junichi, Sadoshima
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Reverse Remodeling With Left Ventricular Assist Devices.
Circulation Research, 2021 This review provides a comprehensive overview of the past 25+ years of research into the development of left ventricular assist device (LVAD) to improve clinical outcomes in patients with severe end-stage heart failure and basic insights gained into the ...
D. Burkhoff +3 more
semanticscholar +1 more source
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020 Background Pulmonary hypertension (PH) results in increased right ventricular (RV) afterload and ventricular remodeling. Sacubitril/valsartan (sac/val) is a dual acting drug, composed of the neprilysin inhibitor sacubitril and the angiotensin receptor ...
Danial Sharifi kia +5 more
semanticscholar +1 more source
Computational modeling of acute myocardial infarction [PDF]
, 2016 This is an Accepted Manuscript of an article published by Taylor & Francis Group in Computer Methods in Biomechanics and Biomedical Engineering on October, 2016, available online at: http://www.tandfonline.com/10.1080/10255842.2015.1105965Myocardial ...
Kuhl, E., Sáez Viñas, Pablo
core +2 more sources
JACC: Basic to Translational Science, 2019 Summary: After myocardial infarction, remote ventricular remodeling and atrial cardiomyopathy progress despite successful revascularization. In a rat model of ventricular ischemia/reperfusion, pharmacological inhibition of the protease activity of ...
Mathias Hohl, PhD +13 more
doaj +1 more source
Soluble ST2 levels and left ventricular structure and function in patients with metabolic syndrome [PDF]
, 2016 Background: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family.
Beunza, Maite +14 more
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Circulation Cardiovascular Imaging, 2020 Supplemental Digital Content is available in the text. Background Cardiac right ventricular remodeling plays a substantial role in pathogenesis, progression, and prognosis of pulmonary hypertension.
Yang Dong +11 more
semanticscholar +1 more source
Left Ventricular Reverse Remodeling in Heart Failure: Remission to Recovery
, 2021 Increased left ventricular dilation and reduced systolic function are consistently associated with a poor prognosis and worse clinical outcomes.
J. Boulet, M. Mehra
semanticscholar +1 more source