Results 21 to 30 of about 123,523 (307)

Prevalence and significance of alterations in cardiac structure and function in patients with heart failure and a preserved ejection fraction [PDF]

open access: yes, 2011
<p><b>Background:</b> The purpose of this study was to examine the prevalence of abnormalities in cardiac structure and function present in patients with heart failure and a preserved ejection fraction (HFPEF) and to determine whether ...
Michel Komajda   +18 more
core   +1 more source

THE ROLE OF ECHOCARDIOGRAPHY IN ASSESSMENT OF HEART REMODELING IN PATIENTS WITH CTEPH

open access: yesЕвразийский Кардиологический Журнал, 2016
SUMMERY The study included 40 patients with CTEPH of different severity. All patients underwent 2D and 3D echocardiography to assess structure and function of right and left heart chambers, ventricular interaction, and ventricular-vascular coupling.
A. A. Belevskaya   +3 more
doaj   +1 more source

Pinocembrin Decreases Ventricular Fibrillation Susceptibility in a Rat Model of Depression

open access: yesFrontiers in Pharmacology, 2020
Background: Depression is associated with the increased risk of mortality and morbidity and is an independent risk factor for many cardiovascular diseases. Depression may promote cardiac arrhythmias, but little is known about the mechanisms.
Tianxin Ye   +35 more
doaj   +1 more source

HDAC5 inhibition attenuates ventricular remodeling and cardiac dysfunction

open access: yesOrphanet Journal of Rare Diseases, 2023
Background This study aimed to investigate the role of histone deacetylase 5 (HDAC5) in ventricular remodeling and explore the therapeutic potential of the HDAC5 inhibitor LMK235. Methods A transverse aortic constriction (TAC) mouse model and angiotensin
Chenxi Zhu, Zhehao Piao, Li Jin
doaj   +1 more source

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]

open access: yes, 2012
Background: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti- inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
Juhász Viktor   +36 more
core   +1 more source

Effects of transverse aortic constriction-induced left ventricular dysfunction on pulmonary vascular remodeling in rats and its relationship with bone morphogenetic protein 7

open access: yesDi-san junyi daxue xuebao, 2020
Objective To study the effects of left ventricular dysfunction induced by transverse aortic constriction (TAC) on pulmonary vascular remodeling and hemodynamics, and the relationship with bone morphogenetic protein 7 (BMP7) expression in the lung tissues
HU Junhao   +5 more
doaj   +1 more source

HDAC-dependent ventricular remodeling [PDF]

open access: yesTrends in Cardiovascular Medicine, 2013
Heart failure, a syndrome culminating the pathogenesis of many forms of heart disease, is highly prevalent and projected to be increasingly so for years to come. Major efforts are directed at identifying the means of preventing, slowing, or possibly reversing the unremitting progression of pathological stress leading to myocardial injury and ultimately
Min, Xie, Joseph A, Hill
openaire   +2 more sources

Correlation Between Endothelial Dysfunction and Left Ventricular Remodeling in Patients with Chronic Kidney Disease

open access: yesKidney & Blood Pressure Research, 2014
Background/Aims: To investigate the role of endothelial dysfunction on left ventricular remodeling in patients with chronic kidney disease and to evaluate the correlation between endothelial dysfunction and left ventricular remodeling.
Tao Peng   +4 more
doaj   +1 more source

Dual Endothelin Receptor Blockade Abrogates Right Ventricular Remodeling and Biventricular Fibrosis in Isolated Elevated Right Ventricular Afterload. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:Pulmonary arterial hypertension is usually fatal due to right ventricular failure and is frequently associated with co-existing left ventricular dysfunction. Endothelin-1 is a powerful pro-fibrotic mediator and vasoconstrictor that is elevated
Eva Amalie Nielsen   +5 more
doaj   +1 more source

Traditional Chinese Medicine Intervenes Ventricular Remodeling Following Acute Myocardial Infarction: Evidence From 40 Random Controlled Trials With 3,659 Subjects

open access: yesFrontiers in Pharmacology, 2021
Objectives: We intend to conduct a meta-analysis on the systematic evaluation of traditional Chinese medicine (TCM) in the treatment of ventricular remodeling following acute myocardial infarction (AMI).
Xiao-Xiao Zhang   +3 more
doaj   +1 more source

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