Pro/Anti-Inflammatory Cytokine Imbalance in Postischemic Left Ventricular Remodeling
Objectives. Cytokines play an important role in left ventricular remodeling consequent to myocardial ischemia. The aim of this study was to correlate cytokine production and lymphocyte apoptosis to post-ischemic left ventricular remodeling in patients ...
Pasqui Anna Laura +6 more
doaj +1 more source
Surgical Ventricular Restoration to Reverse Left Ventricular Remodeling [PDF]
Heart failure is one of the major health care issues in the Western world. An increasing number of patients are affected, leading to a high rate of hospitalization and high costs. Even with administration of the best available medical treatment, mortality remains high. The increase in left ventricular volume after a myocardial infarction is a component
Castelvecchio, Serenella +2 more
openaire +2 more sources
Significance of myocardial tenascin-C expression in left ventricular remodelling and long-term outcome in patients with dilated cardiomyopathy [PDF]
Aim Dilated cardiomyopathy (DCM) has a variety of causes, and no useful approach to predict left ventricular (LV) remodelling and long-term outcome has yet been established.
Anzai, T +12 more
core +1 more source
Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy. [PDF]
Calcium/calmodulin-dependent protein kinase II (CaMKII) plays a central role in pathological cardiac hypertrophy, but the mechanisms by which it modulates gene activity in the nucleus to mediate hypertrophic signaling remain unclear. Here, we report that
An, Woojin +7 more
core +1 more source
A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease [PDF]
Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF).
Antonio Amodeo +15 more
core +3 more sources
Myocardial infarction (MI) triggers a poor ventricular remodeling response, but the underlying mechanisms remain unclear. Here, the authors show that sentrin‐specific protease 1 (SENP1) is downregulated in post‐MI mice and in patients with severe heart ...
Zhihao Liu +20 more
doaj +1 more source
Right Atrial-to-Right Ventricular Area
Background: Severe secondary tricuspid regurgitation (STR) in heart failure patients is associated with excess mortality. Quantification associated risk assessment, remains challenging, specifically with contextual anatomic variability.
Charlotte Jantsch, MD +14 more
doaj +1 more source
Pulmonary hypertension (PH) is featured by pulmonary vascular and cardiac remodeling. Rehabilitation exercise can improve patients’ quality of life. We previously pinpointed a potential glutamine metabolism dysfunction in PH. Hence, we aim to investigate
Shang Wang +8 more
doaj +1 more source
Adaptations to iron deficiency: cardiac functional responsiveness to norepinephrine, arterial remodeling, and the effect of beta-blockade on cardiac hypertrophy. [PDF]
BackgroundIron deficiency (ID) results in ventricular hypertrophy, believed to involve sympathetic stimulation. We hypothesized that with ID 1) intravenous norepinephrine would alter heart rate (HR) and contractility, 2) abdominal aorta would be larger ...
Chew, Herbert George +8 more
core +1 more source
Background Residence at high altitudes (HAs) may increase cardiovascular risk due to hypobaric hypoxia, but its synergy with pulmonary hypertension cause is unclear.
Wanlin Peng +13 more
doaj +1 more source

