Results 21 to 30 of about 29,656 (290)
Theoretical grounds of integral vectors of ventricular depolarization and repolarization and their sum, i.e., the spatial ventricular gradient, have been studied.
Aidu Eduard A. I., Trunov Vladimir G.
doaj +1 more source
A compact three-dimensional representation of cardiac action potential (AP) properties in terms of current source is presented here. The experimental protocol used to obtain such representation is based on the measure of instantaneous current-voltage ...
Massimiliano Zaniboni +1 more
doaj +1 more source
Calcium-activated potassium current modulates ventricular repolarization in chronic heart failure.
The role of I(KCa) in cardiac repolarization remains controversial and varies across species. The relevance of the current as a therapeutic target is therefore undefined. We examined the cellular electrophysiologic effects of I(KCa) blockade in controls,
Ingrid M Bonilla +14 more
doaj +1 more source
Beat-to-beat variability of ventricular repolarization reveals sex-specific instability and proarrhythmic risk. [PDF]
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Sato D, Santini L, Coppini R, Grandi E.
europepmc +2 more sources
Impact of hypokalemia on electromechanical window, excitation wavelength and repolarization gradients in guinea-pig and rabbit hearts. [PDF]
Normal hearts exhibit a positive time difference between the end of ventricular contraction and the end of QT interval, which is referred to as the electromechanical (EM) window.
Oleg E Osadchii
doaj +1 more source
Diabetes mellitus attenuates the repolarization reserve in mammalian heart
Objective: In diabetes mellitus several cardiac electrophysiological parameters are known to be affected. In rodent experimental diabetes models changes in these parameters were reported, but no such data are available in other mammalian species ...
Lengyel, Csaba Attila +12 more
core +1 more source
Dispersion of ventricular repolarization and refractory period [PDF]
Time for primary review 34 days. In their classic studies published in 1964, Han, Moe and co-workers [1,2] established an association between nonuniform recovery of excitability and lowered fibrillation threshold. They concluded that “those agencies known to favour the development of ventricular fibrillation were found to increase the temporal ...
F L, Burton, S M, Cobbe
openaire +2 more sources
The congenital short QT syndrome (SQTS) is a cardiac condition that leads to abbreviated ventricular repolarization and an increased susceptibility to arrhythmia and sudden death.
Chunyun Du +9 more
doaj +1 more source
RISK STRATIFICATION OF SUDDEN CARDIAC DEATH IN EARLY REPOLARIZATION SYNDROME
The article describes approaches to risk stratification of sudden cardiac death in early ventricular repolarization syndrome, as one of the variants of J-wave syndrome, on the basis of clinical, anamnestic and electrocardiographic criteria.
Shpak N. V. +3 more
doaj +1 more source
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source

