Results 91 to 100 of about 391,145 (293)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Excitation of the Isolated Ventricular Septum of the Heart

Experimental Biology and Medicine, 1951
Conclusions1. It is possible to obtain electrograms on the isolated perfused dog's ventricular septum, and these show a reproducible pattern. 2. The records indicate that the excitatory process in these experiments traveled in a complicated fashion and the pattern varied somewhat from animal to animal. In some of the experiments the excitatory pathways
H B, BURCHELL, R D, PRUITT, H E, ESSEX
openaire   +2 more sources

Molecular genetics of arrhythmogenic right ventricular cardiomyopathy in South Africa [PDF]

, 2011
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable disorder characterised by progressive degeneration of the right ventricular myocardium, arrhythmias and an increased risk of sudden death at a young age. Fourteen chromosomal loci have
Blanckenberg, Janine
core   +1 more source

Case‐malformed signal detection and prioritisation using EUROmediCAT data for pharmacovigilance in pregnancy

British Journal of Clinical Pharmacology, EarlyView.
Aim Many women take medications during pregnancy. However, the risk to the fetus from most medications is uncertain. Congenital anomalies are one of the leading causes of infant death and contribute to long‐term disability. Signal detection methods can be used to systematically identify possible medication–anomaly associations that require further ...
Hannah Johnson, Helen Dolk, Maria Loane, Christine Damase‐Michel, Joanne Given, Hedvig Nordeng, Jorieke E. H. Bergman, Iain Carey, Elly Den Hond, Ester Garne, Florence Rouget, Lea Bruneau, Isabelle Monier, Anke Rissmann, Mary O'Mahony, Miriam Gatt, Renée Lutke, Joanna Sichitiu, Elisa Ballardini, Alessio Coi, Clara Cavero Carbonell, David Tucker, Joan Morris   +22 more
wiley   +1 more source

High implantation technique during CoreValve replacement in a high-risk aortic stenosis patient with a sigmoid left ventricular hypertrophy and a large aortic annulus

Türk Kardiyoloji Derneği Arşivi, 2015
The appropriate size, accurate alignment and correct positioning of transcatheter aortic valves (TAVIs) at the point of deployment are emphasized as key factors in placement and fixation of the devices.
Teoman Kılıç, Ertan Ural, Şadan Yavuz, Tülay Hoşten, Hüseyin İnce   +4 more
doaj   +1 more source

Transthoracic three-dimensional echocardiography for the assessment of straddling tricuspid or mitral valves [PDF]

, 2000
Background The advent of 3D echocardiography has provided a technique which, potentially, could afford significant additional information over conventional cross-sectional echocardiography in the assessment of patients with straddling atrioventricular ...
Anderson, RH, Lincoln, C, Vogel, M, Ho, SY   +3 more
core  

Clinical Anatomy of the Left and Right Atrial Appendages in Humans: Comparative and Developmental Perspective

Clinical Anatomy, EarlyView.
ABSTRACT Human atrial chambers derive from distinct embryonic anlagens, the original embryonic atria gradually transforming into the so‐called auricles, or atrial appendages. This study quantifies macroscopic variations in pectinate muscle architecture in human atrial appendages and evaluates their visualization using clinical imaging modalities.
Markéta Lexová, Caroline Neradilová, Jan Kovanda, Jan Burkert, Jiří Beneš Jr., Martin Bartos, Theodor Adla, Vojtech Melenovsky, Alena Kvasilova, Ondrej Fabian, Ondrej Naňka, David Sedmera   +11 more
wiley   +1 more source

Specialized impulse conduction pathway in the alligator heart

eLife, 2018
Mammals and birds have a specialized cardiac atrioventricular conduction system enabling rapid activation of both ventricles. This system may have evolved together with high heart rates to support their endothermic state (warm-bloodedness) and is ...
Bjarke Jensen, Bastiaan J Boukens, Dane A Crossley II, Justin Conner, Rajiv A Mohan, Karel van Duijvenboden, Alex V Postma, Christopher R Gloschat, Ruth M Elsey, David Sedmera, Igor R Efimov, Vincent M Christoffels   +11 more
doaj   +1 more source

MUSCULAR DEFECTS IN THE VENTRICULAR SEPTUM [PDF]

Heart, 1956
D, HEATH, J W, BROWN, W, WHITAKER
openaire   +2 more sources

Validation of an Automated Artificial Intelligence‐Driven Planner for Transcatheter Aortic Valve Replacement

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Preprocedural planning with multislice computed tomography (MSCT) is an essential prerequisite for successful transcatheter aortic valve replacement (TAVR). However, preprocedural planning is time‐consuming and may contain clinically meaningful interobserver variability.
Mark M. P. van den Dorpel, Lucas Uchoa de Assis, Jenna van Niekerk, Sophie Deckx, Matthew Sherman, Janelle Schrot, Anna Kozak, Isabella Kardys, Alexander Hirsch, Joost Daemen, Rutger Jan Nuis, Nicolas M. Van Mieghem   +11 more
wiley   +1 more source