Results 41 to 50 of about 106,182 (308)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Pulmonary valvulotomy in a fetus with pulmonary atresia with intact ventricular septum : first experience in Turkey [PDF]

, 2012
The mortality and morbidity of children with pulmonary atresia with intact ventricular septum (PA/IVS) is closely related with right ventricle hypoplasia and its consequent hemodynamics.
Danısman, N., Polat, Tugcin Bora
core   +1 more source

A novel closed-chest porcine model of chronic ischemic heart failure suitable for experimental research in cardiovascular disease [PDF]

, 2013
Cardiac pathologies are among the leading causes of mortality and morbidity in industrialized countries, with myocardial infarction (MI) representing one of the major conditions leading to heart failure (HF).
Antonio Amodeo, BIONDI ZOCCAI, GIUSEPPE, CALOGERO, ANTONELLA, CAVARRETTA, Elena, CHIMENTI, ISOTTA, DE FALCO, ELENA, Fabrizio D'Ascenzo, FRATI, GIACOMO, Luca Pacini, MANCONE, Massimo, Maria Emiliana Caristo, MARULLO, Antonino, Marzia Lotrionte, Omar Leoni, PERUZZI, MARIANGELA, PETROZZA, Vincenzo   +15 more
core   +3 more sources

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

The role of contractile dyssynchrony in pacing-induced cardiomyopathy: detailed assessment using index of contractile asymmetry

Cardiovascular Ultrasound, 2023
Aims The pathophysiological effects of chronic right ventricular pacing and the role of right ventricular lead position are not well understood. Therefore, we investigated the association between left ventricular contractile dyssynchrony and pacing ...
Patricia Zerlang Fruelund, Anders Sommer, Søren Lundbye-Christensen, Claus Graff, Peter Søgaard, Sam Riahi, Tomas Zaremba   +6 more
doaj   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Congenital Aneurysmal Tunnel of the Trabecular Muscular Interventricular Septum or a Partially Closed Ventricular Septal Defect? A Case Report with Review of Literature

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging
Isolated congenital aneurysm-like deformity of the muscular interventricular septum is rare and may be associated with other congenital heart defects, ventricular dysfunction, conduction disturbances, and chromosomal abnormalities. It may be a partial or
Madhu Shukla, Jagdish Chander Mohan
doaj   +1 more source

Ruptura del septum ventricular como complicación de un evento coronario agudo

Revista Colombiana de Cardiología, 2017
La ruptura del septum ventricular (RSV) es una complicación mecánica infrecuente del infarto agudo de miocardio (IAM). Los principales factores de riesgo descritos son la edad avanzada, el género femenino, un primer episodio de IAM y la presencia de ...
William J. Morales-Camacho, José M. Chilatra-Fonseca, Jessica E. Plata-Ortiz, Yisela P. Gómez-Mancilla, Andrea N. Villabona-Suárez, Sergio A. Villabona-Rosales   +5 more
doaj   +1 more source

Angiography‐guided mid/high septal implantation of ventricular leads in patients with congenital heart disease

Journal of Arrhythmia, 2021
Background Conduction system pacing prevents pacing‐induced cardiomyopathy, but it can be challenging to perform in patients with congenital heart disease (CHD), and mid/high septal lead implantation is an alternative.
Jayaprakash Shenthar, Sanjai P. Valappil, Maneesh K. Rai, Bharatraj Banavalikar, Deepak Padmanabhan, Tammo Delhaas   +5 more
doaj   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source