Results 61 to 70 of about 103 (103)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang +13 more
wiley +1 more source
Beyond Earth: Resilience of Quasi‐2D Perovskite Solar Cells in Space
In the article (DOI: 10.1002/adma.202520433), Christoph Putz and co‐workers demonstrate rigid quasi‐2D perovskite solar cells operating in low Earth orbit, delivering stable power for more than 100 days under real‐space conditions. In‐orbit performance is correlated with extensive ground‐based thermal and proton‐irradiation studies on rigid and ...
Christoph Putz +17 more
wiley +1 more source
Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz +2 more
wiley +1 more source
The study evaluated the vulnerability and adaptation status of farming households in the climate‐sensitive wetland region of Bangladesh, using survey data from 120 households. The livelihood vulnerability index indicated moderate vulnerability (0.53), with key risks stemming from livelihood strategies, natural resource dependence and climatic ...
Farhana Yasmin Bithi +6 more
wiley +1 more source
Mu Opioid Receptor mRNA and Protein Localization Across the Rat and Mouse Habenula
Mu opioid receptor (MOR) mRNA was detected with RNAscope in situ hybridization for Oprm1 and protein was detected with immunocytochemistry to map the distributions across the anterior‐posterior extent of the rat and mouse habenula. Expression distribution was also characterized in a transgenic reporter mouse line (Oprm1‐Venus/Venus) as an additional ...
Aashka K. Popat +6 more
wiley +1 more source
Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley +1 more source
ABSTRACT Although objectification is prevalent in leadership relations, little is known about (a) why some supervisors objectify their employees to a greater extent than others and (b) when and how such objectification manifests in a supervisor's leadership behavior.
Katerina Tsantila, Frank Walter
wiley +1 more source
AB‐MDMSBA—Not a Synthetic Cannabinoid Receptor Agonist
This study uses classical in vitro pharmacology approaches to establish that AB‐MDMSBA does not bind to or activate the cannabinoid CB1 receptor and therefore should not be classified as a synthetic cannabinoid receptor agonist. ABSTRACT Synthetic cannabinoids remain one of the most prominent classes of New Psychoactive Substances (NPS).
Monica Patel +4 more
wiley +1 more source
Abstract In Low Earth Orbit (LEO), atmospheric drag is the dominant source of trajectory prediction error below approximately 700 km altitude, primarily due to inaccuracies in thermospheric density models. This work presents a method for temporally deconvolving Energy Dissipation Rates (EDRs) to produce single‐satellite density estimates, which can be ...
S. Mutschler +6 more
wiley +1 more source

