Results 61 to 70 of about 103 (103)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang   +13 more
wiley   +1 more source

Beyond Earth: Resilience of Quasi‐2D Perovskite Solar Cells in Space

open access: yesAdvanced Materials, Volume 38, Issue 31, 2 June 2026.
In the article (DOI: 10.1002/adma.202520433), Christoph Putz and co‐workers demonstrate rigid quasi‐2D perovskite solar cells operating in low Earth orbit, delivering stable power for more than 100 days under real‐space conditions. In‐orbit performance is correlated with extensive ground‐based thermal and proton‐irradiation studies on rigid and ...
Christoph Putz   +17 more
wiley   +1 more source

Erasable FAP Targeted Spray‐On Probe for Fluorescence‐Guided Surgery

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
We present the first erasable spray‐on probe for fluorescence‐guided surgery. Following topical delivery, FAP‐FLASH550 targets fibroblast activation protein–expressing stromal cells, delineating tumor margins with high tumor‐to‐background ratios. A 365 nm UV light pulse rapidly erases fluorescent signals through triazene photodegradation and subsequent
Zachary Rabinowitz   +2 more
wiley   +1 more source

Determinants of Household Adaptation to Climate Vulnerability in Wetland Areas of Bangladesh: An Empirical Estimation

open access: yesClimate Resilience and Sustainability, Volume 5, Issue 1, June 2026.
The study evaluated the vulnerability and adaptation status of farming households in the climate‐sensitive wetland region of Bangladesh, using survey data from 120 households. The livelihood vulnerability index indicated moderate vulnerability (0.53), with key risks stemming from livelihood strategies, natural resource dependence and climatic ...
Farhana Yasmin Bithi   +6 more
wiley   +1 more source

Mu Opioid Receptor mRNA and Protein Localization Across the Rat and Mouse Habenula

open access: yesJournal of Comparative Neurology, Volume 534, Issue 6, June 2026.
Mu opioid receptor (MOR) mRNA was detected with RNAscope in situ hybridization for Oprm1 and protein was detected with immunocytochemistry to map the distributions across the anterior‐posterior extent of the rat and mouse habenula. Expression distribution was also characterized in a transgenic reporter mouse line (Oprm1‐Venus/Venus) as an additional ...
Aashka K. Popat   +6 more
wiley   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

open access: yesFood Biomacromolecules, Volume 3, Issue 2, Page 237-251, June 2026.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Some of Them Want to Use You: Antecedents and Consequences of Supervisors' Employee‐Directed Objectification

open access: yesJournal of Organizational Behavior, Volume 47, Issue 5, Page 786-807, June 2026.
ABSTRACT Although objectification is prevalent in leadership relations, little is known about (a) why some supervisors objectify their employees to a greater extent than others and (b) when and how such objectification manifests in a supervisor's leadership behavior.
Katerina Tsantila, Frank Walter
wiley   +1 more source

AB‐MDMSBA—Not a Synthetic Cannabinoid Receptor Agonist

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
This study uses classical in vitro pharmacology approaches to establish that AB‐MDMSBA does not bind to or activate the cannabinoid CB1 receptor and therefore should not be classified as a synthetic cannabinoid receptor agonist. ABSTRACT Synthetic cannabinoids remain one of the most prominent classes of New Psychoactive Substances (NPS).
Monica Patel   +4 more
wiley   +1 more source

First Results of a New Inversion Tool for Thermospheric Neutral Mass Density Computations During Severe Geomagnetic Storms

open access: yesAGU Advances, Volume 7, Issue 3, June 2026.
Abstract In Low Earth Orbit (LEO), atmospheric drag is the dominant source of trajectory prediction error below approximately 700 km altitude, primarily due to inaccuracies in thermospheric density models. This work presents a method for temporally deconvolving Energy Dissipation Rates (EDRs) to produce single‐satellite density estimates, which can be ...
S. Mutschler   +6 more
wiley   +1 more source

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