Results 171 to 180 of about 101,449 (340)

Calcineurin Inhibitor Associated Nephrotoxicity in Kidney Transplantation—A Transplant Nephrologist's Perspective

open access: yesActa Physiologica, Volume 241, Issue 5, May 2025.
ABSTRACT Aim Calcineurin inhibitors (CNIs) have revolutionized transplant medicine, improving allograft survival but posing challenges like calcineurin inhibitor‐induced nephrotoxicity (CNT). Acute CNT, often dose‐dependent, leads to vasoconstriction and acute kidney injury, with treatment focusing on CNI exposure reduction.
Carla M. Hansen   +4 more
wiley   +1 more source

Frequency Analysis of Atrial Fibrillation From the Surface Electrocardiogram [PDF]

open access: yes, 2004
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Neither the natural history of AF nor its response to therapy are sufficiently predictable by clinical and echocardiographic parameters.
Bollmann, Andreas   +4 more
core  

Untargeted metabolomics reveals novel metabolites in Lotus japonicus roots during arbuscular mycorrhiza symbiosis

open access: yesNew Phytologist, Volume 246, Issue 3, Page 1256-1275, May 2025.
Summary Arbuscular mycorrhiza (AM) improves mineral nutrient supply, stress tolerance, and growth of host plants through re‐programing of plant physiology. We investigated the effect of AM on the root secondary metabolome of the model legume Lotus japonicus using untargeted metabolomics. Acetonitrile extracts of AM and control roots were analysed using
Josef L. Ranner   +9 more
wiley   +1 more source

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

open access: yesAdvanced Therapeutics, Volume 8, Issue 4, April 2025.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap   +10 more
wiley   +1 more source

Comparative Effects of Verapamil, Nifedipine, and Diltiazem on Contractile Function in the Isolated Immature and Adult Rabbit Heart [PDF]

open access: bronze, 1984
Robert J. Boucek   +5 more
openalex   +1 more source

Mitral Annulus Disjunction Causing Ventricular Tachyarrhythmias in a Young Lady With Palpitations, Cardiac Ablation Terminated the Complaints

open access: yesClinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Mitral annulus disjunction (MAD) is a rare but significant cause of ventricular arrhythmias in young patients. Timely diagnosis using cardiac magnetic resonance imaging and targeted management with catheter ablation can effectively control arrhythmias, improve patient outcomes, and prevent severe complications such as sudden cardiac death.
Mohammad Hosein Nikoo   +3 more
wiley   +1 more source

Effects of verapamil on atrial fibrillation and its electrophysiological determinants in dogs [PDF]

open access: yes, 2017
Background: Atrial tachycardia-induced remodeling promotes the occurrence and maintenance of atrial fibrillation (AF) and decreases L-type Ca2+ current. There is also a clinical suggestion that acute L-type Ca2 channel blockade can promote AF, consistent
Bénardeau, Agnès   +2 more
core  

SLO2.1/NALCN Functional Complex Activity in Mouse Myometrial Smooth Muscle Cells During Pregnancy

open access: yesJournal of Cellular Physiology, Volume 240, Issue 4, April 2025.
ABSTRACT At the end of pregnancy, the uterus transitions from a quiescent to a highly contractile state. This is partly due to the depolarization of the resting membrane potential in uterine (myometrial) smooth muscle cells (MSMCs). In human MSMCs, the membrane potential is regulated by a functional complex between the sodium (Na+)‐activated potassium (
Juan J. Ferreira   +11 more
wiley   +1 more source

Hypertension [PDF]

open access: yes, 2004
Hypertension is a rapidly moving clinical field with frequent developments in new pharmacologic agents and management strategies. Perhaps more importantly, there have been substantial improvements in our understanding of how best to use the drugs ...
Farrugia, Emanuel
core  

Home - About - Disclaimer - Privacy