Results 181 to 190 of about 12,316 (253)
Scandinavian Journal of Caring Sciences, Volume 40, Issue 3, September 2026.ABSTRACT Background Older adults living in institutional long‐term care (ILTC) generally have decreased mobility, and their mobility care is often insufficient. Residents spend much of their day being sedentary, even though sedentary behaviour and inactivity are known to have many negative effects on health and functional capacity.
Johanna Finskas +3 more
wiley +1 more source
Mixed-methods study assessing the accuracy of verbal autopsy and sociocultural determinants of infant mortality in Gujarat, India. [PDF]
J Educ Health PromotPatel M +5 more
europepmc +1 more source
Mapping Trofinetide Polypharmacology in Rett Syndrome: A Multi‐Stage Computational Analysis
Journal of Computational Chemistry, Volume 47, Issue 21, August 5, 2026.How can a single molecule address the complex symptoms of Rett syndrome? This computational study maps the multi‐target mechanism of trofinetide, revealing diverse modes of binding across five key receptors: GAT1, GABAA, CHRM1, AMPA, and GSK3β. From deep orthosteric anchoring to dynamic surface interactions, these structural insights provide a rational
Luis Felipe Hernández‐Ayala +2 more
wiley +1 more source
Synthesizing a pragmatic and systemized measure of universal health coverage: verifying the circumstances of mortality CATegories of death investigated by verbal autopsy. [PDF]
Front Public HealthZhu N +4 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1543-1557, August 2026.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Validation of malaria-attributed deaths using verbal autopsy studies: a systematic review. [PDF]
Malar JCarshon-Marsh R +3 more
europepmc +1 more source
Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review
Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1530-1542, August 2026.ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi +7 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION Animal models demonstrated that pharmacologically‐induced lesioning of the locus coeruleus (LC), the brain's primary source of norepinephrine, triggered astrocyte reactivity, exacerbating Alzheimer's disease (AD) pathology and cognitive deficits.
Prokopis C. Prokopiou +11 more
wiley +1 more source
Hormone replacement therapy and its association with LATE‐NC in older adults
Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.Abstract INTRODUCTION Limbic‐predominant age‐related transactive response DNA‐binding protein 43 (TDP‐43) encephalopathy neuropathological change (LATE‐NC) is a cause of dementia resembling Alzheimer's disease (AD). The 90+ Study found women using hormone replacement therapy (HRT) two to three decades before death had lower odds of LATE‐NC.
Yohana M. Kim +6 more
wiley +1 more source