Sleep apnea in REM sleep as an amplifier of vascular contributions to Alzheimer's disease
Abstract Obstructive sleep apnea (OSA), a common though underdiagnosed disorder in older adults, represents a potential upstream vascular stressor linked to increased Alzheimer's disease (AD) risk. In this Perspective article, we propose a stage‐informed framework in which rapid eye movement (REM) sleep‐related respiratory events amplify vascular ...
Destiny E. Berisha +2 more
wiley +1 more source
Estimating annual deaths from stroke in adults under 70 years of age in Freetown Sierra Leone: A comparative analysis of a hospital-based stroke register and a population-based verbal autopsy study. [PDF]
Youkee D +9 more
europepmc +1 more source
Prospective study on physical activity and Alzheimer's disease–related biomarkers
Abstract INTRODUCTION Evidence regarding the association between physical activity (PA) and Alzheimer's disease (AD)–related biomarkers is scarce and inconsistent. METHODS At ages 56 and 67, 564 men from the Vietnam Era Twin Study of Aging reported their PA during the preceding week from which metabolic equivalent of energy expenditure (MET) hours were
Paula Iso‐Markku +11 more
wiley +1 more source
Accuracy of the Verbal Autopsy questionnaire in the diagnosis of COVID-19 deaths in a Brazilian capital. [PDF]
Campos MAG +7 more
europepmc +1 more source
Abstract INTRODUCTION Plasma p‐tau217 and p‐tau217/Aβ42 reliably identify non‐Hispanic White individuals with symptomatic and pre‐clinical AD. However, performance across ethnoracially diverse groups remains unknown. METHODS Cognitively normal Black, Hispanic, and non‐Hispanic White participants completed cognitive evaluations, brain magnetic resonance
Yoav D Piura +11 more
wiley +1 more source
Comparison of causes of stillbirth and child deaths as determined by verbal autopsy and minimally invasive tissue sampling. [PDF]
Assefa N +34 more
europepmc +1 more source
Purpose To evaluate bilateral isokinetic performance symmetry of knee extensors and flexors 6 months after anterior cruciate ligament reconstruction using a rectus femoris tendon autograft. Methods This retrospective case series included patients consecutively recruited at a single tertiary sports medicine center between January 2023 and July 2024 ...
Alef Cavalcanti Matias de Barros +8 more
wiley +1 more source
Perceptions of healthcare workers on implementing the 2022 WHO verbal autopsy instrument in rural India through the existing public health system. [PDF]
Tripathi S +9 more
europepmc +1 more source
Prescribing competence: The pros and cons of different methods for assessment
Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman +3 more
wiley +1 more source
Mortality in children and adolescents in Western Democratic Republic of Congo: retrospective analysis of verbal autopsy and demographic data from the Kimpese Health and Demographic Surveillance System. [PDF]
Fumwakwau JK +7 more
europepmc +1 more source

