Results 181 to 190 of about 37,961 (305)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
VeriFed: Temporally Consistent Continuous Cross-Chain Data Federation. [PDF]
Entropy (Basel)Hao K, Bi M, Ma Y.
europepmc +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Non-Interactive and Information-Theoretic Secure Publicly Verifiable Secret Sharing
, 2008 A publicly verifiable secret sharing scheme is more applicable than a verifiable secret sharing because of the property that the validity of the shares distributed by the dealer can be verified by any party.
Zhuojun Liu Yong He +2 more
core
When advance directives clash with family consent: designing an operational framework for end-of-life decision-making in China and Korea. [PDF]
BMC Med EthicsLuo S, Cho D, Cho J.
europepmc +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Zero-Knowledge Process Verification: A Comprehensive Framework for a Distributed Healthcare System. [PDF]
Blockchain Healthc TodayKrishnasamy S.
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
A Prospective Clinical Evaluation of Combined Targeted Verifiable Subcision and Helium Plasma Radiofrequency for the Treatment of Cellulite and Skin Laxity. [PDF]
Aesthet Surg J Open ForumDiBernardo BE.
europepmc +1 more source