Results 201 to 210 of about 459,587 (231)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Beyond translation: A review into preserving human connection in AI-mediated health language interpretation. [PDF]

PLOS Digit Health
Kokorelias KM, Metersky K, Reppas-Rindlisbacher C, Al-Hamad A.   +3 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Assessment of Bone Resection Accuracy in Robotic-Arm-Assisted Total Knee Arthroplasty: A Prospective Observational Study. [PDF]

J Orthop Case Rep
Gundalli AC, Singh A, Kumar P, Kalyan K, Mane SS, Swarnkar H.   +5 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Ethical Aspects in Clinical Practice: Recommended Summary Plan for Emergency Care and Treatment (ReSPECT) Conversations and Death Certification Processes Among NHS Clinicians. [PDF]

Cureus
Balar U, Chauhan R, Patel RN.
europepmc   +1 more source

The value of 3D contrast-enhanced CT radiomics in predicting response to neoadjuvant chemotherapy for adenocarcinoma of the esophagogastric junction: a two-center study. [PDF]

BMC Cancer
Luo C, Li J, Mu W, Yuan M, Zhan P, Liu Y, Zhou Y, Li L, Ding C, Chen X, Gao J.   +10 more
europepmc   +1 more source

Performance Verification of High Sensitivity Analyzer for TAT, PIC, TM, and t-PAIC. [PDF]

TH Open
Liu Y, Guo B, Chen G, Chen C, Meng Z, Xie Y, Fan Y, Ma R, Gao L.   +8 more
europepmc   +1 more source

Contactless biometric verification from in-air signatures using deep siamese networks. [PDF]

Sci Rep
Salturk S, Pamukcu TE, Kahraman N.
europepmc   +1 more source