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Vernal Keratoconjunctivitis (VKC)
Ocular Immunology and Inflammation, 1993Vernal keratoconjunctivitis (VKC) is an allergic ocular disease in children and young adults. It is linked to atopy but it is characterized by typical inflammatory changes of ocular tissues. The conjunctiva often shows hyperplasia, with infiltration of lymphocytes and eosinophils; also mast cells, confined to the substantia propria in normal subjects ...
S, Bonini, S, Bonini
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Acta Ophthalmologica Scandinavica, 1999
Vernal keratoconjunctivitis therefore, if managed properly, can be controlled. Inaccurate diagnosis or staging of the disease, together with inaccurate treatment will however, result in changes which can jeopardize sight and may even necessitate corneal surgery at a later date.
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Vernal keratoconjunctivitis therefore, if managed properly, can be controlled. Inaccurate diagnosis or staging of the disease, together with inaccurate treatment will however, result in changes which can jeopardize sight and may even necessitate corneal surgery at a later date.
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Limbal vernal keratoconjunctivitis in the tropics
Ophthalmology, 1998This study aimed to describe the pathology of vernal keratoconjunctivitis (VKC) in children from Kenya.Case series.Ten patients with clinically active and untreated limbal VKC and five age-matched control subjects without external eye disease were recruited from a district eye hospital in Kenya.Paraffin sections of limbal and tarsal conjunctiva were ...
S J, Tuft +3 more
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Immunopathological study of vernal keratoconjunctivitis
Graefe's Archive for Clinical and Experimental Ophthalmology, 1989The in situ immune reaction occurring in the conjunctival tissues of patients with vernal keratoconjunctivitis was studied using immunohistochemical techniques and a panel of monoclonal and polyclonal antibodies. Our data point to a complex immunopathogenesis of the disease. The anaphylactic response was demonstrated by the presence of many eosinophils
A M, Abu el-Asrar +5 more
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Immunogenetic investigation in vernal keratoconjunctivitis
Pediatric Allergy and Immunology, 2014Vernal keratoconjunctivitis has been considered a multifac- torial condition resulting from complex interactions among genetic, immunologic, and environmental factors. The research of genetic characteristics and the identification of a specific HLA haplotype as a possible predictor of disease may contribute to elucidate the pathogenesis of the disease ...
ZICARI, Anna Maria +8 more
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[Vernal keratoconjunctivitis].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2015Vernal keratoconjunctivitis (VKC) is a bilateral, usually seasonally recurrent inflammation of the conjunctiva. Clinically characteristic findings are tarsal giant conjunctival papillae (> 1 mm) and/or limbal gelatinous changes (Trantas dots).
U, Pleyer, A, Leonardi
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Topical Cyclosporine in Vernal Keratoconjunctivitis
Ophthalmology, 1991In a placebo-controlled, double-masked clinical trial, the authors evaluated the effects of topical 2% cyclosporine on 20 patients with vernal keratoconjunctivitis (VKC). Nineteen patients were male and one was female. Patients ranged in age from 5 to 19 years (mean, 9.7 years).
J H, Bleik, K F, Tabbara
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A contribution to the immunopathology of vernal keratoconjunctivitis
Documenta Ophthalmologica, 1982The tear fluid contains proteins which are synthesized locally in the conjunctiva and lacrimal glands, and others, which reach the tear fluid from the blood circulation. It is generally accepted that serum albumin (HSA) belongs to the latter group of tear proteins.
D, Sompolinsky +3 more
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Corneal Ectasia in Vernal Keratoconjunctivitis
Ophthalmology, 1989The type of corneal ectasia, the presence of breaks in Descemet's membrane, and the success with contact lens wear or penetrating keratoplasty were studied in 61 patients with corneal ectasia and vernal keratoconjunctivitis. There were 53 patients with keratoconus, 5 with pellucid marginal corneal degeneration, 2 with keratoglobus, and 1 with superior ...
J A, Cameron, A A, Al-Rajhi, I A, Badr
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