Results 1 to 10 of about 2,804 (212)

Vernonia amygdalina Ethanol Extract Protects against Doxorubicin-Induced Cardiotoxicity via TGFβ, Cytochrome c, and Apoptosis [PDF]

Molecules, 2023
Doxorubicin (DOX) has been extensively utilized in cancer treatment. However, DOX administration has adverse effects, such as cardiac injury. This study intends to analyze the expression of TGF, cytochrome c, and apoptosis on the cardiac histology of ...
Rony Abdi Syahputra, Urip Harahap, Yahdiana Harahap, Andayana Puspitasari Gani, Aminah Dalimunthe, Amer Ahmed, Satirah Zainalabidin   +6 more
doaj   +4 more sources

Vernonia amygdalina protects against doxorubicin-induced hepatic and renal damage in rats: mechanistic insights [PDF]

Pharmacia, 2023
The use of the chemotherapeutic agent doxorubicin is limited due to its potential to cause signifi-cant hepatorenal damage. The present study aimed to investigate the potential hepatoprotective and nephroprotective effects of Vernonia amygdalina, a ...
Arya Tjipta Prananda, Aminah Dalimunthe, Urip Harahap, Rony Abdi Syahputra, Sony Eka Nugraha, Putri Cahaya Situmorang, Yee Teck Fah, Adrian Joshua Velaro, Besa Bilakaya, Muhammad Andika Yudha Harahap   +9 more
doaj   +6 more sources

In vivo anticoccidial activity and immune response of Moringa oleifera and Vernonia amygdalina leaves against Eimeria magna and Eimeria media in rabbits [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionThe aims of this study were to determine the immune response and the anticoccidial activity induced by Moringa oleifera and Vernonia amygdalina leaves in rabbits infected with Eimeria magna and Eimeria media.MethodsThirty-five-day-old rabbits,
Basile Konmy, Basile Konmy, Basile Konmy, Pascal Abiodoun Olounladé, Pascal Abiodoun Olounladé, Tomabu Adjobimey, Christian Cocou Dansou, Akouavi Carine Chimène Adoho, Esaïe Tchetan, Esaïe Tchetan, Georcelin Goué Alowanou, Erick Virgile Bertrand Azando, Adolphe Adjanohoun, Sanni-yo Doko Allou, Lamine Baba-Moussa   +14 more
doaj   +2 more sources

Early Assessment of the Invasiveness of the Alien Plant <i>Vernonia amygdalina</i> Del. Introduced in China. [PDF]

Ecol Evol
This study evaluates the invasion potential of Vernonia amygdalina by synthesizing evidence on its taxonomic background, morphological and life‐history traits, reproductive strategies, allelopathic effects, defense mechanisms, climatic suitability, and human‐mediated introduction and cultivation practices.
Gao L, Deng JL, Liu SN, Ma YL.
europepmc   +2 more sources

Crude Extract and Phenol-Rich Fractions from Vernonia amygdalina Leaves Ameliorates Streptozotocin-Induced Type 1 Diabetes in Rats by Mitigating Hepatic Injury, Dyslipidemia, and Production of Oxido-Inflammatory Markers [PDF]

Journal of Xenobiotics
Diabetes mellitus (DM) is a major disorder contributing to human mortality and morbidity globally. The use of medicinal plants in the management of diabetes is gaining global popularity due to their accessibility and cost-effectiveness. In this study, we
Olawale Razaq Ajuwon, Damilola Rebecca Oladejo, Akinwunmi Oluwaseun Adeoye, John Adeolu Falode, Basiru Olaitan Ajiboye, Foluso Oluwagbemiga Osunsanmi, Babatunji Emmanuel Oyinloye   +6 more
doaj   +2 more sources

Neuro-protective and Neuro-curative effect of Vernonia Amygdalina in rat model of neurodegenerative disease [PDF]

Journal of Trace Elements and Minerals, 2023
Background: In this study, we assessed the protective potential of Vernonia amygdalina methanolic extract on aluminum chloride- induced neurotoxicity damage in Wistar rats.
A.O Ajeleti, G.G Akunna, J.H Ojo, A. Irozuoke   +3 more
doaj   +2 more sources

The anticancer activities of Vernonia amygdalina Delile. Leaves on 4T1 breast cancer cells through phosphoinositide 3-kinase (PI3K) pathway

Heliyon, 2020
Vernonia amygdalina Delile (Asteraceae) is used in traditional medicine to treat diabetes mellitus, and some research provides its activity to treat breast cancer.
Urip Harahap, Denny Satria, Panal Sitorus   +2 more
exaly   +3 more sources

ANTIOXIDANT ACTIVITY TEST OF AFRICAN LEAVES PURIFICATION EXTRACT (Vernonia amygdalina Del) WITH DPPH METHOD

Jurnal Farmasi Sains dan Praktis, 2023
African leaves (Vernonia amygdalina Del) is a plant that can be used as a medicinal plant because it contains flavonoid compounds that are effective as natural antioxidants that can suppress free radicals.
Nina Karlina, Aan Kunaedi, Didin Ahidin, Uzlifatul Jannah, Yasmin Zahiyah   +4 more
doaj   +1 more source

Phytochemical Analysis and Assessment of Antibacterial Efficacy of Vernonia amygdalina (Bitter Leaf) against Some Selected Clinical Bacterial Isolates

UMYU Journal of Microbiology Research, 2023
Vernonia amygdalina is a plant known to contain substances with reported antimicrobial properties against various microorganisms. This study therefore, aimed at assessing the antibacterial properties of Vernonia amygdalina extract against some clinical ...
Auwal Magaji, Zinat Mahmud, Aminu Mustafa   +2 more
doaj   +1 more source

Antibacterial activities of plant leaf extracts against multi-antibiotic resistant Staphylococcus aureus associated with skin and soft tissue infections

BMC Complementary Medicine and Therapies, 2022
Background The antibacterial activities of aqueous leaf extracts of Moringa oleifera, Vernonia amygdalina, Azadirachta indica and Acalypha wilkesiana against multidrug resistance (MDR) Staphylococcus aureus associated with skin and soft tissue infections
P. A. Akinduti, V. Emoh-Robinson, H. F. Obamoh-Triumphant, Y. D. Obafemi, T. T. Banjo   +4 more
doaj   +1 more source