Results 151 to 160 of about 7,300,025 (237)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Publicaciones en versión accesible [PDF]

De acuerdo con la estrategia de inclusión de la discapacidad, 2021-2025, de la Comisión Económica para América Latina y el Caribe (CEPALDIS), la Comisión está produciendo publicaciones en versión accesible para satisfacer las necesidades de accesibilidad

core   +1 more source

Co-Designing an Easy-Read Adult Social Care Outcomes Measure for Older People: Approach to and Reflections on Involving People Living With Dementia and Their Supporters. [PDF]

Health Expect
Mikelyte R, Oliver K, Oliver R, Caiels J, Rand S, Field E, Webster L, Towers AM.   +7 more
europepmc   +1 more source

Atrial Tachycardia Utilizing Bachmann's Bundle as an Epicardial Bypass: A Case Suggestive of a Dual-Loop Mechanism. [PDF]

Ann Noninvasive Electrocardiol
Sakurai R, Nakatani Y, Fujiwara K, Miyamoto T.   +3 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Descripción de cuatro casos por mordedura de araña atribuibles a Loxosceles rufescens (Araneae, Sicariidae) en España: revisión bibliográfica, identificación, biología, vigilancia y control integrado

Revista de Salud Ambiental
A pesar de la mala fama y reputación de las arañas, la realidad es que su mordedura ocurre de manera accidental y es peligrosa únicamente en un número muy limitado de casos.
Mikel alexander González, Carlos Pradera, Rubén de Blas, Juan Emilio Testa, Miguel Angel Miranda, Carlos Barceló   +5 more
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Correction: Teaching medical ethics and medical professionalism in Saudi public and private medical schools. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Towards Automated Spine Fracture Detection on Whole-Body CT of Polytraumatized Patients. [PDF]

J Imaging
Stojanovski E, Hönning A, Spohn F, Ciesla M, Arndt H, Mutze S, Golla AK, Klinder T, Lorenz C, Goelz L.   +9 more
europepmc   +1 more source