Results 91 to 100 of about 416,381 (343)

Gastrula‐Premarked Posterior Enhancer Primes Posterior Tissue Development Through Cross‐Talk with TGF‐β Signaling Pathway

Advanced Science, EarlyView.
A gastrula‐premarked enhancer within the first intron of Cdx2 governs posterior embryonic development via both regulating Cdx2 expression in cis and coordinating TGF‐β signaling in trans to ensure proper posterior body development. Functional rescue in gastruloids reveals a Cdx2‐independent pathway, highlighting p‐Enh‐eRNA as key epigenetic ...
Yingying Chen, Fengxiang Tan, Qing Fang, Lin Zhang, Jiaoyang Liao, Penglei Shen, Yun Qian, Mingzhu Wen, Rui Song, Yonggao Fu, He Jax Xu, Ran Wang, Cheng Li, Zhen Shao, Jinsong Li, Naihe Jing, Xianfa Yang   +16 more
wiley   +1 more source

Ontogenetic stomach development in catshark Scyliorhinus canicula.

Frontiers in Marine Science, 2015
The gastrointestinal tract (GIT) of vertebrates develops from a simple undifferentiated tube into highly differentiated regions for the digestion and absorption of nutrients.
Odete Goncalves, Odete Goncalves, Renata Freitas, Sylvie Mazan, Jonathan M Wilson   +4 more
doaj   +1 more source

Phylotranscriptomic consolidation of the jawed vertebrate timetree

Nature Ecology & Evolution, 2017
Phylogenomics is extremely powerful but introduces new challenges as no agreement exists on ‘standards’ for data selection, curation and tree inference. We use jawed vertebrates (Gnathostomata) as a model to address these issues.
Iker Irisarri, D. Baurain, H. Brinkmann, Frédéric Delsuc, J. Sire, A. Kupfer, Jörn Petersen, M. Jarek, A. Meyer, M. Vences, H. Philippe   +10 more
semanticscholar   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Host ecotype and rearing environment are the main drivers of threespine stickleback gut microbiota diversity in a naturalistic experiment

Royal Society Open Science
Host–microbiota interactions play a critical role in the hosts’ biology, and thus, it is crucial to elucidate the mechanisms that shape gut microbial communities.
Andreas Härer, Christine J. Frazier, Diana J. Rennison   +2 more
doaj   +1 more source

Membrane Proteins Mediating Reception and Transduction in Chemosensory Neurons in Mosquitoes

Frontiers in Physiology, 2018
Mosquitoes use chemical cues to modulate important behaviors such as feeding, mating, and egg laying. The primary chemosensory organs comprising the paired antennae, maxillary palps and labial palps are adorned with porous sensilla that house primary ...
Jackson T. Sparks, Gina Botsko, Daniel R. Swale, Linda M. Boland, Shriraj S. Patel, Joseph C. Dickens   +5 more
doaj   +1 more source

Two Rounds of Whole Genome Duplication in the Ancestral Vertebrate

PLoS Biology, 2005
The hypothesis that the relatively large and complex vertebrate genome was created by two ancient, whole genome duplications has been hotly debated, but remains unresolved.
Paramvir S. Dehal, J. Boore
semanticscholar   +1 more source

Testosterone Delays Bone Microstructural Destruction via Osteoblast‐Androgen Receptor‐Mediated Upregulation of Tenascin‐C

Advanced Science, EarlyView.
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie, Meng Pan, Zeyuan Zhang, Licheng Zhang, Haotian Liu, Xia Wang, William W Lu, Peifu Tang, Wei Ge   +8 more
wiley   +1 more source

Global importance of vertebrate pollinators for plant reproductive success: a meta-analysis

, 2018
Vertebrate pollinators are increasingly threatened worldwide, but little is known about the potential consequences of their declines for plants and wider ecosystems.
Fabrizia Ratto, Benno I. Simmons, Rebecca Spake, V. Zamora‐Gutierrez, M. MacDonald, Jennifer C. Merriman, C. Tremlett, G. Poppy, K. Peh, L. Dicks   +9 more
semanticscholar   +1 more source

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

Advanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li, Xinzhu Li, Xiao Xiang, Jundong Huang, Xinyu Shen, Mengyue Wang, Jingwei Jiang, Shiwen Shao, Zeming Li, Tian Xie, Deming Liu, Yiping Zhao, Rui Ma, Wenyu Wu, Wei Shi, Cheng‐Ming Chuong, Ji Li, Mingxing Lei   +17 more
wiley   +1 more source