Results 121 to 130 of about 416,381 (343)

Long‐Read Whole‐Genome Sequencing Uncovers a Deletion Upstream to HOXD13 Causing Synpolydactyly

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Synpolydactyly (SPD) is a heterogeneous distal‐limb malformation syndrome, characterized by webbing and duplication of adjacent digits. SPD1, the most common type, is attributed to disease‐causing variants in HOXD13, a transcription factor in the HOXD cluster that is essential for limb development. Here, we present a challenging exome‐negative
Jonathan Rips   +9 more
wiley   +1 more source

Pharmacological properties of the repellent secretion of Zonocerus variegatus (L.) (Orthoptera: Prygomorphidae)

open access: yesRevista de Biología Tropical, 1999
The odours of the whole body and the secretion of Zonocerus variegatus were easily recognised and perceived by human volunteers. However, the secretion odour is not related to the odour of the food plant consumed by the grasshopper.
A.B Idowu, O.A Idowu
doaj  

Comparative analysis of palmitoylation sites of serotonin (5‐HT) receptors in vertebrates

open access: yesNeuropsychopharmacology Reports, 2018
Background In the vertebrate central nervous system as well as in the periphery, serotonin, also known as 5‐hydroxytriptamine (5‐HT), function as a neurotransmitter, a hormone or a mitogen.
Toshie Kaizuka, Takashi Hayashi
doaj   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo   +2 more
wiley   +1 more source

Three Periods of Regulatory Innovation During Vertebrate Evolution

open access: yesScience, 2011
C. B. Lowe   +8 more
semanticscholar   +1 more source

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