Results 241 to 250 of about 416,381 (343)

A single-cell atlas of the bobtail squid visual and nervous system highlights molecular principles of convergent evolution. [PDF]

Nat Ecol Evol
Gavriouchkina D, Tan Y, Parey E, Ziadi-Künzli F, Hasegawa Y, Piovani L, Zhang L, Sugimoto C, Luscombe N, Marlétaz F, Rokhsar DS.   +10 more
europepmc   +1 more source

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

Animal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li, Yanyan Sun, Jingwei Yuan, Xiangchen Li, Lei Shi, Adamu Mani Isa, Yuanmei Wang, Pingzhuang Ge, Yunhe Zong, Panlin Wang, Jilan Chen   +10 more
wiley   +1 more source

The Quest for Antibodies and Other Acquired Immune Receptors: A Historical Perspective. [PDF]

Int J Immunogenet
De Lerma Barbaro A, Balkhi S, Giovannardi S, Vianelli A, Ribatti D, Mortara L.   +5 more
europepmc   +1 more source

Regulation of Chondrocyte Metabolism and Osteoarthritis Development by Sirt5 Through Protein Lysine Malonylation

Arthritis &Rheumatology, EarlyView.
Objective Chondrocytemetabolic dysfunction plays an important role in osteoarthritis (OA) development during aging and obesity. Protein posttranslational modifications (PTMs) have recently emerged as an important regulator of cellular metabolism. We aim to study one type of PTM, lysine malonylation (MaK), and its regulator sirtuin 5 (Sirt5) in OA ...
Huanhuan Liu, Anupama Binoy, Siqi Ren, Thomas C. Martino, Anna E. Miller, Craig R. G. Willis, Shivakumar R. Veerabhadraiah, Joanna Bons, Jacob P. Rose, Birgit Schilling, Michael J. Jurynec, Shouan Zhu   +11 more
wiley   +1 more source

The global distribution patterns of alien vertebrate richness in mountains. [PDF]

Nat Commun
García-Rodríguez A, Lenzner B, Velasco JA, Schertler A, Omer A, Seebens H, Capinha C, Gallardo B, Dullinger S, Essl F.   +9 more
europepmc   +1 more source

Active DNA demethylation at enhancers during the vertebrate phylotypic period

Nature Genetics, 2016
O. Bogdanović, A. H. Smits, Elisa de la Calle Mustienes, J. Tena, E. Ford, Ruth M. Williams, Upeka Senanayake, Matthew D. Schultz, S. Hontelez, Ila van Kruijsbergen, Teresa Rayon, Felix A Gnerlich, T. Carell, G. Veenstra, M. Manzanares, T. Sauka-Spengler, J. Ecker, M. Vermeulen, J. Gómez-Skarmeta, R. Lister   +19 more
semanticscholar   +1 more source

Approaches to repurposing reverse transcriptase antivirals in cancer

British Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head, Saiful Islam, Jennifer H. Martin   +2 more
wiley   +1 more source

Implications From the Analogous Relationship Between Evolutionary and Learning Processes

BioEssays, EarlyView.
Organismal evolution resembles learning processes in many aspects, but the analogy has not been widely recognized. We discuss new opportunities inspired by this analogy to enhance predictive capabilities and theoretical developments in both research fields, especially using white‐box modeling for expanding predictive theory in evolutionary biology ...
Jason Cheok Kuan Leong, Masaaki Imaizumi, Hideki Innan, Naoki Irie   +3 more
wiley   +1 more source

Evolutionary History of Bilaterian FoxP Genes: Complex Ancestral Functions and Evolutionary Changes Spanning 2R-WGD in the Vertebrate Lineage. [PDF]

Mol Biol Evol
Tsai FY, Lin CY, Su YH, Yu JK, Kuo DH.
europepmc   +1 more source