Results 51 to 60 of about 416,381 (343)

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Taurine Promotes Neurite Outgrowth and Synapse Development of Both Vertebrate and Invertebrate Central Neurons

Frontiers in Synaptic Neuroscience, 2020
Taurine is a sulfur-containing amino acid that is widely expressed throughout the human brain, heart, retina, and muscle tissues. Taurine deficiency is associated with cardiomyopathy, renal dysfunction, abnormalities of the developing nervous system, and
Brittany Mersman, Brittany Mersman, Wali Zaidi, Naweed I. Syed, Fenglian Xu, Fenglian Xu   +5 more
doaj   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Gluconeogenesis in the yolk syncytial layer‐like tissue of cloudy catshark (Scyliorhinus torazame)

Physiological Reports
Glucose has important roles in the development of zebrafish, the vertebrate animal model; however, in most oviparous animals, the amount of maternally provided glucose in the yolk is scarce.
Marino Shimizu, Wataru Takagi, Yuki Sakai, Isana Kayanuma, Fumiya Furukawa   +4 more
doaj   +1 more source

A Comparative Genomics Study on the Molecular Evolution of Serotonin/Melatonin Biosynthesizing Enzymes in Vertebrates

Frontiers in Molecular Biosciences, 2020
Serotonin is important in vertebrates for its crucial roles in regulation of various physiological functions. Investigations on how the biosynthesizing enzymes mediate serotonin production and conversion during biological processes have been active in ...
Yunyun Lv, Yanping Li, Yanping Li, Jia Li, Chao Bian, Chuanjie Qin, Qiong Shi   +6 more
doaj   +1 more source

The whale shark genome reveals patterns of vertebrate gene family evolution

eLife, 2021
Chondrichthyes (cartilaginous fishes) are fundamental for understanding vertebrate evolution, yet their genomes are understudied. We report long-read sequencing of the whale shark genome to generate the best gapless chondrichthyan genome assembly yet ...
Milton Tan, Anthony K Redmond, Helen Dooley, Ryo Nozu, Keiichi Sato, Shigehiro Kuraku, Sergey Koren, Adam M Phillippy, Alistair DM Dove, Timothy Read   +9 more
doaj   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Urban biodiversity: an insight into the terrestrial vertebrate diversity of Guwahati, India

Journal of Threatened Taxa, 2018
This study focuses on the assessment of the terrestrial vertebrate diversity of Guwahati.  Twenty-six species of amphibians, 57 species of reptiles, 214 species of birds, and 36 species of mammals were recorded during the study period.
Jayaditya Purkayastha
doaj   +1 more source

Comparative Analyses of Vertebrate Gut Microbiomes Reveal Convergence between Birds and Bats

mBio, 2020
Diet and host phylogeny drive the taxonomic and functional contents of the gut microbiome in mammals, yet it is unknown whether these patterns hold across all vertebrate lineages.
Se Jin Song, Jon G. Sanders, Frédéric Delsuc, Jessica Metcalf, Katherine Amato, Michael W. Taylor, Florent Mazel, Holly L. Lutz, Kevin Winker, Gary R. Graves, Gregory Humphrey, Jack A. Gilbert, Shannon J. Hackett, Kevin P. White, Heather R. Skeen, Sarah M. Kurtis, Jack Withrow, Thomas Braile, Matthew Miller, Kevin G. McCracken, James M. Maley, Vanessa O. Ezenwa, Allison Williams, Jessica M. Blanton, Valerie J. McKenzie, Rob Knight   +25 more
doaj   +1 more source

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

Genes & Development, 1996
A recurrent theme in embryonic development and tissue regeneration is that cells communicate with each other using just a handful of conserved families of signaling molecules.
B. Hogan
semanticscholar   +1 more source