Results 71 to 80 of about 416,381 (343)

Amphioxus functional genomics and the origins of vertebrate gene regulation

open access: yesNature, 2018
Vertebrates have greatly elaborated the basic chordate body plan and evolved highly distinctive genomes that have been sculpted by two whole-genome duplications.
Ferdinand Marlétaz   +60 more
semanticscholar   +1 more source

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

open access: yesAdvanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He   +16 more
wiley   +1 more source

Vertebral replacement for the treatment of vertebral osteosarcoma in a cat

open access: yesJournal of Veterinary Medical Science, 2017
A 7-year-old cat was referred with pelvic limb ataxia. Radiography and CT revealed bone resorption of the L1 vertebral arch, and myelography identified a compressive extradural lesion. The mass was surgically removed and histopathologically diagnosed as giant cell osteosarcoma.
Hiroki Sakai   +7 more
openaire   +4 more sources

Piezoelectric Biomaterials for Bone Regeneration: Roadmap from Dipole to Osteogenesis

open access: yesAdvanced Science, EarlyView.
Piezoelectric biomaterials convert mechanical forces into electrical signals, offering novel strategies to restore and modulate bone microenvironments for tissue engineering. This review examines molecular dipole origins, spatial arrangements, and pseudo‐piezoelectric mechanisms and highlights dipole‐engineering techniques for osteogenesis regulation ...
Xiyao Ni   +7 more
wiley   +1 more source

Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model

open access: yesAdvanced Science, EarlyView.
A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana   +10 more
wiley   +1 more source

Gentle Label‐Free Nonlinear Optical Imaging Relaxes Linear‐Absorption‐Mediated Triplet

open access: yesAdvanced Science, EarlyView.
The phototoxicity in nonlinear optical microscopy arises mainly from linear absorption of intrinsic biomolecules rather than nonlinear absorption. This mechanism is supported by a reproducible phototoxicity assay based on widely available chicken breast.
Geng Wang   +4 more
wiley   +1 more source

Erratum: Roadkills in Northern Peninsular Malaysia

open access: yesFrontiers in Environmental Science, 2022
Frontiers Production Office
doaj   +1 more source

Evolution and Diversity of Transposable Elements in Vertebrate Genomes

open access: yesGenome Biology and Evolution, 2017
Transposable elements (TEs) are selfish genetic elements that mobilize in genomes via transposition or retrotransposition and often make up large fractions of vertebrate genomes.
C. Sotero-Caio   +3 more
semanticscholar   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

open access: yesAdvanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Development of the vertebrate neuromuscular junction.

open access: yesAnnual Review of Neuroscience, 1999
We describe the formation, maturation, elimination, maintenance, and regeneration of vertebrate neuromuscular junctions (NMJs), the best studied of all synapses.
J. Sanes, J. Lichtman
semanticscholar   +1 more source

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