Results 41 to 50 of about 563,489 (286)

The evolution and comparative neurobiology of endocannabinoid signalling [PDF]

, 2012
CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A., Maurice R. Elphick, Montell C., Soderstrom K., Soderstrom K.   +4 more
core   +1 more source

Evolution of astrocytes: From invertebrates to vertebrates

Frontiers in Cell and Developmental Biology, 2022
The central nervous system (CNS) shows incredible diversity across evolution at the anatomical, cellular, molecular, and functional levels. Over the past decades, neuronal cell number and heterogeneity, together with differences in the number and types ...
Carmen Falcone
doaj   +1 more source

The nuclear receptors of Biomphalaria glabrata and Lottia gigantea: Implications for developing new model organisms [PDF]

, 2015
© 2015 Kaur et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Antebi, A Aranda, A Bateman, A Daniel, A De Groot, A Heyland, A Le Maire, AC Chung, AE Lockyer, AE Lockyer, AE Lockyer, AE Lockyer, AE Lockyer, AE Sluder, AK Allen, AM Puinean, Anne E. Lockyer, AP Scott, AP Scott, B Stone, C Shiff, C Thummel, C Tyler, Catherine S. Jones, CB Burge, CJ Carter, CK Glass, CL Hultin, CM Adema, CM Adema, D Bouton, D Jones, D Lima, D Stange, DH Huson, DL Whitehead, E Enmark, Edwin J. Routledge, ER Levin, ES Ford, F Abascal, F Bonneton, F Ronquist, FM Sladek, G Benoit, G Escobedo, G Mitta, GN Eick, GV Markov, GV Markov, H Ueda, H Urushitani, H Zhang, H-R Koehler, I Letunic, J Auwerx, J Gutierrez-Mazariegos, J Keay, J Keay, J Oehlmann, J-M Wurtz, JT Bridgham, JT Bridgham, JW Thornton, K King-Jones, K King-Jones, K Tamura, L Chitsulo, L de F Tallarico, L-M Chen, LA Hertel, Leslie R. Noble, LFC Castro, LFC Castro, LN Rapado, M Garcia, M Kajiwara, M Knight, M Laguerre, M Pawlak, M Robinson-Rechavi, M Robinson-Rechavi, M Robinson-Rechavi, M Tillmann, M-JWA Schiffelers, MD Adams, ME Baker, ME Baker, MI Snow, N Raghavan, NE-SE-S Omran, O Simakov, P Matthiessen, P Matthiessen, P Thomas, PC Hanington, PC Hanington, PD Thomas, Peter P. Fong, PL Bardet, R Bannister, R Bannister, R Lafont, RA Velarde, RJ Greenspan, RM Sternberg, RM Sternberg, RT Yu, S Bertrand, S Kliewer, S Kumkate, S Pascoal, S Vogeler, SA Thomson, Satwant Kaur, SF Altschul, SH Golden, Susan Jobling, T Li, T Matsumoto, T Simoncini, TH Lindblom, TT Schug, W Wu, W Wu, W Wu, W Wu, X Ding, X Mu, Y Katsu, YG Jiang, ZD Zhang   +131 more
core   +4 more sources

Vertebrate Skeletogenesis [PDF]

, 2010
Vertebrate skeletogenesis consists in elaborating an edifice of more than 200 pieces of bone and cartilage. Each skeletal piece is crafted at a distinct location in the body, is articulated with others, and reaches a specific size, shape, and tissue composition according to both species instructions and individual determinants. This complex, customized
Véronique, Lefebvre, Pallavi, Bhattaram
openaire   +2 more sources

Vertebrate innovations [PDF]

Proceedings of the National Academy of Sciences, 2000
Vertebrate innovations include neural crest cells and their derivatives, neurogenic placodes, an elaborate segmented brain, endoskeleton, and an increase in the number of genes in the genome. Comparative molecular and developmental data give new insights into the evolutionary origins of these characteristics and the complexity of the vertebrate ...
Shimeld, S, Holland, P
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Vertebrates...and the conflicts in public image [PDF]

, 1974
The author explores human perceptions, as influenced by words and the images they conjure in the human brain. People worldwide have formed strong images relating to our environment, both positive and negative: beauty and splendor vs.
Haraldstad, Tormod, Haugen, Thrond Oddvar, Hawley, Kate Louise, Höglund, Erik, Kroglund, Frode, Olsen, Esben Moland   +5 more
core  

Vertebrate palaeophysiology [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2020
Physiology is a functional branch of the biological sciences, searching for general rules by which explanatory hypotheses are tested using experimental procedures, whereas palaeontology is a historical science dealing with the study of unique events where conclusions are drawn from congruence among independent lines of evidence.
Jorge Cubo, Adam K. Huttenlocker
openaire   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A Comparative Biology of Microglia Across Species

Frontiers in Cell and Developmental Biology, 2021
Microglia are unique brain-resident, myeloid cells. They have received growing interest for their implication in an increasing number of neurodevelopmental, acute injury, and neurodegenerative disorders of the central nervous system (CNS).
Kaushik Sharma, Kaushik Sharma, Kanchan Bisht, Kanchan Bisht, Ukpong B. Eyo, Ukpong B. Eyo   +5 more
doaj   +1 more source