Results 41 to 50 of about 352,814 (314)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Faunal Remains From Diang Mahang In Kalimantan: Taxonomic Identification And Their Archaeological Context

Pubawidya: Jurnal Penelitian dan Pengembangan Arkeologi, 2022
Faunal remains, both vertebrates and invertebrates, are important discoveries in archaeological research. Such proxy may provide information on the identity of animal species which may associate with human at a site.
Vida Pervaya Rusianti Kusmartono, Ni Luh Gde Dyah Mega Hafsari   +1 more
doaj   +1 more source

At the transition from invertebrates to vertebrates a novel GnRH-like peptide emerges in amphioxus

, 2014
This work was supported by a grant from the Canadian Natural Sciences and Engineering Council (NSERC).Gonadotropin-releasing hormone (GnRH) is a critical reproductive regulator in vertebrates.
Roch, Graeme, Sherwood, Nancy, Tello, Javier   +2 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Rigor Mortis in Farmed Common Carp Cyprinus carpio: The Effects of Handling Temperature

International Journal of Food Science
The study was conducted to determine the rigor mortis in common carp Cyprinus carpio, weighing 1100±163 g and measuring 37.5±1.87 cm in total length. Immediately after catching, the fish were killed by a blow to the head, followed by washing with tap ...
A. A. Mohammed, A. Y. Jassim, A. T. Yesser, Q. H. Al-Hamadany   +3 more
doaj   +1 more source

The programmed DNA elimination and formation of micronuclei in germ line cells of the natural hybridogenetic water frog Pelophylax esculentus

Scientific Reports, 2018
DNA elimination is a radical form of gene silencing and occurs both in somatic and germ cells. The programmed DNA elimination occurs during gametogenesis in interspecies hybrids that reproduce by hybridogenesis (stick insects, fishes, and amphibians) and
Magdalena Chmielewska, Dmitry Dedukh, Katarzyna Haczkiewicz, Beata Rozenblut-Kościsty, Mikołaj Kaźmierczak, Krzysztof Kolenda, Ewa Serwa, Agnieszka Pietras-Lebioda, Alla Krasikova, Maria Ogielska   +9 more
doaj   +1 more source

Yellow patterns polymorphism of the fire salamander Salamandra salamandra in Poland

Acta Herpetologica, 2018
We analysed variation of dorsal yellow patterns in 2077 individuals that represented 23 populations from the northern parts of the Sudetes and the Carpathian Mountains. We distinguished four types of yellow patterns: spotted (50.1%), spotted-and-striped (
Anna Najbar, Agnieszka Konowalik, Bartłomiej Najbar, Maria Ogielska   +3 more
doaj   +1 more source

Highly conserved elements discovered in vertebrates are present in non-syntenic loci of tunicates, act as enhancers and can be transcribed during development [PDF]

, 2013
Co-option of cis-regulatory modules has been suggested as a mechanism for the evolution of expression sites during development. However, the extent and mechanisms involved in mobilization of cisregulatory modules remains elusive.
Meola, Nicola, Basu, Swaraj, Roure A, Brown, Euan R, Hadzhiev, Y., Brown E, Lemaire P, Amore, G., Strähle, U., Simone, M. de, Hadzhiev, Yavor, Stupka E., Müller F, Banfi, Sandro, Roure, A., Birney, E., Gueroult-Bellone, Marion, De Simone, Marco, Gueroult-Bellone, M., Amore, Gabriele, Roure, Agnes, Ferg M, Licastro, Danilo, Basu, S., Petrera, F., Sanges, R., Brown, Euan R., Gueroult Bellone M, Sanges R, Stupka, Elia, Ferg, Marco, Strähle U, Lemaire, P., Müller, F., Strahle, Uwe, Birney, Ewan, Brown, Euan R; id_orcid, Brown, E. R., Basu S, Stupka, E., Muller, Ferenc, De Simone M, Petrera, Francesca, Petrera F, Lemaire, Patrick, Licastro, D., Sanges, Remo, Hadzhiev Y, Banfi, S., Meola N, Meola, N., Licastro D, Ferg, M., Amore G, Birney E   +54 more
core   +1 more source